5,5'-Difluoro BAPTA-AM

Specifications / Handling

More Information
Product Details
Synonyms	5FBAPTA-AM; 1,2-Bis(2-amino-5-fluorophenoxy)ethane-N,N,N',N'-tetraacetic acid tetrakis(acetoxymethyl) ester
Product Type	Chemical
Properties
Formula	C₃₄H₃₈F₂N₂O₁₈
MW	800.66
CAS	128255-42-5
Source/Host Chemicals	Synthetic
Purity Chemicals	≥97% (HPLC)
Appearance	White to off-white crystalline powder.
Solubility	Soluble in DMSO, DMF, EtOAc or CHCl3.
Identity	Determined by ¹H-NMR.
Declaration	Manufactured by Chemodex.
Other Product Data	Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet.
InChi Key	ZXXWTKAFGAXGHZ-UHFFFAOYSA-N
Smiles	O=C(OCOC(C)=O)CN(CC(OCOC(C)=O)=O)C1=CC=C(F)C=C1OCCOC2=CC(F)=CC=C2N(CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O
Shipping and Handling
Shipping	AMBIENT
Short Term Storage	-20°C
Long Term Storage	-20°C
Handling Advice	Protect from light and moisture.
Use/Stability	Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS	Inquire
Product Specification Sheet
Datasheet	Download PDF

Product-specific References

Description

5,5′-Difluoro-BAPTA-AM is a calcium chelator that may be used to modulate calcium levels and flow within cells to study calcium homeostasis and cell signaling. It is used to study cytosolic free Ca2+ by 19F-NMR. It has high selectivity for Ca2+, it is not particularly pH sensitive and is available protected as its acetoxymethyl ester. Determination with 5,5′-Difluoro-BAPTA-AM are not sensitive to cells which have a high natural background fluorescence.

Product References

(1) G.A. Smith, et al.; PNAS 80, 7178 (1983) | (2) E. Marban, et al.; Circul. Res. 66, 1255 (1990) | (3) P.E. Morris; Org. Prep. Proc. Int. 25, 445 (1993) | (4) A.R. Waldeck, et al.; Eur. Biophys. J. 27, 247 (1998)

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