6-Bromo-3-carboxycoumarin

6-Bromocoumarin-3-carboxylic acid (UBP608) is a halogenated coumarin derivative used as a versatile intermediate in organic synthesis and chemical research. Its bromine substituent and carboxylic acid functionality provide multiple reactive sites for further derivatization, making it valuable in the preparation of fluorescent probes, bioactive molecules, and specialty materials. This compound is commonly applied in medicinal chemistry, dye chemistry, and coumarin-based scaffold development, and it has also attracted interest in biological research as a potential inhibitor scaffold. UBP608 was described as a NMDA receptor family allosteric modulator that selectively inhibits GluN1/GluN2A receptors with a 23-fold selectivity compared to GluN1/GluN2D receptors.