Chemodex

O-Phosphorylethanolamine

CHF 81.00
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CDX-C0021-G02525 gCHF 81.00
CDX-C0021-G100100 gCHF 285.00
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Product Details
Synonyms Colaminephosphoric acid; 2-Aminoethyl dihydrogen phosphate; O-Phosphocolamine; O-Phosphoethanolamine; Monoaminoethyl Phosphate; NSC 254167; PE-104; PEA
Product Type Chemical
Properties
Formula C2H8NO4P
MW 141.06
CAS 1071-23-4
RTECS KJ5830000
Source/Host Chemicals Synthetic
Purity Chemicals ≥98% (HPLC)
Appearance White to off-white powder.
Solubility Soluble in water (50mg/ml).
Identity Determined by 1H-NMR.
Declaration Manufactured by Chemodex.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

InChi Key SUHOOTKUPISOBE-UHFFFAOYSA-N
Smiles OP(OCCN)(O)=O
Shipping and Handling
Shipping AMBIENT
Short Term Storage +20°C
Long Term Storage -20°C
Handling Advice Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
Description

Phosphorylethanolamine is an ethanolamine derivative that is used in the synthesis of two different categories of phospholipids, glycerophospholipid and sphingophospholipid. It is used as an artificial AP-substrate in a TAMRA/TAMRA fluorescence-quenching assay. Newly discovered „phosphoethanolamine cellulose“ has been shown to regulate biofilm matrix architecture and function and might be important understanding bacterial biofilms and for the generation of new cellulosic materials. Synthetic phosphorylethanolamine (PHO-S) has recently demonstrated cytotoxic activity on melanoma tumor cells associated with apoptotic effects, without any effect on normal cells, as such human normal endothelial, fibroblasts and lymphocytes cells. It has shown to have in vitro and in vivo anti-leukemia effects.

Product References

(1) A.T. Myller, et al.; Appl. Surf. Sci. 257, 1616 (2010) | (2) A.K. Ferreira, et al.; Br. J. Cancer 109, 2819 (2013) | (3) A. Shiba, et al.; Sensors 17, E1877 (2017) | (4) A.C.L. Luna, et al.; BMC Res. Notes 11, 126 (2018) | (5) W. Thongsomboon, et al.; Science 359, 334 (2018)

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