Cookie Policy: This site uses cookies to improve your experience. You can find out more about our use of cookies in our Privacy Policy. By continuing to browse this site you agree to our use of cookies.
Chemodex
5(6)-Carboxy-2',7'-difluorofluorescein
As low as
103
CHF
CHF 103.00
In stock
Only %1 left
CDX-C0262-M05050 mgCHF 103.00
NEW
| Product Details | |
|---|---|
| Product Type | Chemical |
| Properties | |
| Formula | C21H12F2O7 |
| MW | 414.32 |
| CAS | 251450-64-3 |
| Source/Host Chemicals | Synthetic |
| Purity Chemicals | ≥95% (NMR) |
| Appearance | Red powder. |
| Solubility | Soluble in DMSO. |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | DDDAACFHCLQORF-UHFFFAOYSA-N |
| Smiles | OC(C(F)=C1)=CC2=C1C3(C(C=CC=C4)=C4C(O3)=O)C5=CC(F)=C(O)C=C5O2.CC(O)=O |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
5(6)-Carboxy-2',7'-difluorofluorescein is a fluorinated fluorescein used as a fluorescent dye used as a building block for synthesis of fluorescent probes. It is a replacement for the widely used carboxyfluorescein and fluorescein isothiocyanate since the absorption and emission are virtually unchanged. It can be excited with the 488nm spectral line of the argon-ion laser used in flow cytometers and confocal laser scanning microscopes. The lower pKa, increased resistance to photobleaching, high quantum yield, and diminished quenching on protein conjugation make the dyes superior to other fluoresceins for bioconjugation. Spectral data: Absoprtion 492nm, Emmision 516nm
Product References
(1) W.-C. Sun, et al.; J. Org. Chem. 62, 6469 (1997) | (2) N.G. Norager, et al.; ACS Chem. Biol. 8, 2033 (2013)