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Chemodex
Clindamycin hydrochloride
As low as
71
CHF
CHF 71.00
In stock
Only %1 left
CDX-C0324-G01010 gCHF 71.00
CDX-C0324-G02525 gCHF 148.00
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| Product Details | |
|---|---|
| Synonyms | (7S)-7-Chloro-7-deoxylincomycin hydrochloride; NSC-756696; U21251F; Cleocin |
| Product Type | Chemical |
| Properties | |
| Formula | C18H33ClN2O5S . HCl |
| MW | 461.44 |
| CAS | 21462-39-5 |
| RTECS | GF2275000 |
| Source/Host Chemicals | Synthetic |
| Purity Chemicals | ≥97% (TLC) |
| Appearance | White to off-white powder. |
| Solubility | Soluble in water (50mg/ml) or DMSO (50mg/ml). |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | AUODDLQVRAJAJM-XJQDNNTCSA-N |
| Smiles | O[C@H]1[C@@H](SC)O[C@]([H])([C@@H]([C@H](C)Cl)NC([C@]2([H])C[C@@H](CCC)CN2C)=O)[C@H](O)[C@@H]1O.Cl |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +20°C |
| Long Term Storage | +4°C |
| Handling Advice | Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at +4°C. |
| Documents | |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
Clindamycin hydrochloride is a semi-synthetic, lincosamide antibiotic that is prepared from lincomycin. It inhibits bacterial protein synthesis by hydrogen bond interactions with the 23S rRNA component of the 50S ribosomal subunit thus inducing dissociation of the peptidyl-t-RNA complex. It has antibacterial activity against Gram-positive cocci and antiprotozoal activity against Taxoplasma. Clindamycin is used to study bacterial infections, such as group B streptococcal disease, bacterial resistance and plasma protein binding and used to study bacterial protein synthesis.
Product References
(1) M. Smieja; Can. J. Inf. Dis. Med. Microbiol. 9, 22 (1998) | (2) W.S. Champney; Curr. Drug Targets Infect. Disord. 1, 19 (2001) | (3) B. Lell & P.G. Kremsner; Antimicr. Agents Chemother. 46, 2315 (2002) | (4) J. Spizek & T. Rezanka; Appl. Microbiol. Biotech. 64, 455 (2004) | (5) J. Spizek, et al.; Adv. Appl. Microbiol. 56, 121 (2004) | (6) E.S.R. Darley & A.P. MacGowan; J. Antimicrob. Chemother. 53, 928 (2004) | (7) D.N. Wilson; Nat. Rev. Microbiol. 12, 35 (2014)