Chemodex

Choline chloride

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CDX-C0381-G100100 gCHF 45.00
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Product Details
Synonyms (2-Hydroxyethyl)trimethylammonium chloride; Hepacholine; Biocolina; Lipotril
Product Type Chemical
Properties
Formula C5H14ClNO
MW 139.62
CAS 67-48-1
Source/Host Chemicals Synthetic
Purity Chemicals ≥97%
Appearance White to off-white powder.
Solubility Soluble in DMSO, ethanol or DMF (all 20mg/ml).
Identity Determined by 1H-NMR.
Declaration Manufactured by Chemodex.
Other Product Data

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Our product description may differ slightly from the original manufacturer's product datasheet.

InChi Key SGMZJAMFUVOLNK-UHFFFAOYSA-M
Smiles C([N+](C)(C)C)CO.[Cl-]
Shipping and Handling
Shipping AMBIENT
Short Term Storage +20°C
Long Term Storage +20°C
Handling Advice Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at RT.
Documents
Product Specification Sheet
Datasheet Download PDF
Description
Choline is an essential micronutrient critical for cellular and organismal homeostasis. As a core component of phospholipids and sphingolipids, it is indispensable for membrane architecture and function. Additionally, choline is a precursor for acetylcholine, a key neurotransmitter, and betaine, a methyl donor important for epigenetic regulation. Consistent with its pleiotropic role in cellular physiology, choline metabolism contributes to numerous developmental and physiological processes in the brain, liver, kidney, lung and immune system, and both choline deficiency and excess are implicated in human disease. Choline chloride is widely used in scientific research as a source of choline in cell culture media, where it supports membrane biosynthesis and methyl group metabolism.
Product References
(1) L.M. Sanders & S.H. Zeisel; Nutr. Today 42, 181 (2007) | (2) E. Derbyshire & R. Obeid; Nutrients 12, 1731 (2020) | (3) A. Moretti, et al.; Nutrients 12, E2144 (2020) | (4) J. Korbecki, et al.; Int. J. Cancer 156, 1314 (2025) | (5) T.C. Kenny, et al.; Nat. Metab. 7, 35 (2025)
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