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Chemodex
6-Chloropurine
61
CHF
CHF 61.00
In stock
CDX-C0684-G0055 gCHF 61.00
CDX-C0684-G02525 gCHF 244.00
| Product Details | |
|---|---|
| Synonyms | 6-Chloro-9H-purine |
| Product Type | Chemical |
| Properties | |
| Formula |
C5H3ClN4 |
| MW | 154.56 |
| CAS | 87-42-3 |
| RTECS | UO7520000 |
| Source/Host Chemicals | Synthetic |
| Purity Chemicals | ≥98% (HPLC) |
| Appearance | Light yellow powder. |
| Solubility | Soluble in DMSO (20mg/ml). |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | ZKBQDFAWXLTYKS-UHFFFAOYSA-N |
| Smiles | ClC1=C2C(NC=N2)=NC=N1 |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | +4°C |
| Handling Advice | Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at +4°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
6-Chloropurine is a building block in chemical synthesis and is used as an intermediate in the preparation of 9-alkylpurines via alkylation with various substituted alkyl halides in DMSO. 6-Chloropurine based compounds have been shown to display antiviral and antitumor properties.
Product References
(1) A.C. Sartorelli, et al.; J. Pharmacol. Exp. Ther. 134, 123 (1961) | (2) J.A. Montgomery & C. Temple; JACS 83, 630 (1961) | (3) M. Fuertes, et al.; Tetrahedron 26, 4823 (1970) | (4) I.Y. Hwang, et al.; J. Pharmacol. Exp. Ther. 264, 41 (1993) | (5) E. Kierzek & R. Kierzek; Curr. Protoc. Nucleic Acid Chem. Chapter 4, Unit 4.23 (2004) | (6) P. Plackova, et al.; J. Enzyme Inhib. Med. Chem. 30, 57 (2015) | (7) S. Schwarz, et al.; Eur. J. Med. Chem. 90, 595 (2015)