Chemodex

Cinchocaine

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CDX-C0694-G0055 gCHF 54.00
CDX-C0694-G01010 gCHF 102.00

Specifications / Handling

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Product Details
Synonyms Dibucaine; NSC 159055; 2-Butoxy-N-(2-(diethylamino)ethyl)quinoline-4-carboxamide
Product Type Chemical
Properties
Formula C20H29N3O2
MW 343.46
CAS 85-79-0
RTECS GD3150000
Source/Host Chemicals Synthetic
Purity Chemicals ≥97%
Appearance White to off-white powder.
Solubility Soluble in ethanol, chloroform or DMSO. Insoluble in water.
Identity Determined by 1H-NMR.
Declaration Manufactured by Chemodex.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

InChi Key PUFQVTATUTYEAL-UHFFFAOYSA-N
Smiles O=C(NCCN(CC)CC)C1=CC(OCCCC)=NC2=CC=CC=C21
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS Download PDF Download PDF
Product Specification Sheet
Datasheet Download PDF Download PDF

Scientific Background Information

Product Description

Cinchocaine is an amide local anesthetic. It is among the most potent and toxic of the long-acting local anesthetics, by blocking sodium channels. Shown to be a calpain activator inducing platelet apoptosis and to induce apoptosis in leukemia cells. This compound can be used as a reference compound.

Product-specific References

(1) A. Fisher & R. Bryce-Smith; Anaesthesia 26, 324 (1971) | (2) K. Arita, et al.; Biochem. Pharmacol. 60, 905 (2000) | (3) H.A. Douglas, et al.; J. Neurophysiol. 105, 1482 (2011) | (4) W. Zhang, et al.; Int. J. Mol. Sci. 12, 2125 (2011) | (5) K. Tonooka, et al.; Forensic Sci. Int. 265, 182 (2016)

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