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Chemodex
Cinchocaine
Product Details | |
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Synonyms | Dibucaine; NSC 159055; 2-Butoxy-N-(2-(diethylamino)ethyl)quinoline-4-carboxamide |
Product Type | Chemical |
Properties | |
Formula | C20H29N3O2 |
MW | 343.46 |
CAS | 85-79-0 |
RTECS | GD3150000 |
Source/Host Chemicals | Synthetic |
Purity Chemicals | ≥97% |
Appearance | White to off-white powder. |
Solubility | Soluble in ethanol, chloroform or DMSO. Insoluble in water. |
Identity | Determined by 1H-NMR. |
Declaration | Manufactured by Chemodex. |
Other Product Data |
Click here for Original Manufacturer Product Datasheet |
InChi Key | PUFQVTATUTYEAL-UHFFFAOYSA-N |
Smiles | O=C(NCCN(CC)CC)C1=CC(OCCCC)=NC2=CC=CC=C21 |
Shipping and Handling | |
Shipping | AMBIENT |
Short Term Storage | +4°C |
Long Term Storage | -20°C |
Handling Advice | Protect from light and moisture. |
Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
Documents | |
MSDS | Download PDF |
Product Specification Sheet | |
Datasheet | Download PDF |
Cinchocaine is an amide local anesthetic. It is among the most potent and toxic of the long-acting local anesthetics, by blocking sodium channels. Shown to be a calpain activator inducing platelet apoptosis and to induce apoptosis in leukemia cells. This compound can be used as a reference compound.
(1) A. Fisher & R. Bryce-Smith; Anaesthesia 26, 324 (1971) | (2) K. Arita, et al.; Biochem. Pharmacol. 60, 905 (2000) | (3) H.A. Douglas, et al.; J. Neurophysiol. 105, 1482 (2011) | (4) W. Zhang, et al.; Int. J. Mol. Sci. 12, 2125 (2011) | (5) K. Tonooka, et al.; Forensic Sci. Int. 265, 182 (2016)