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Chemodex
Chlorogenic acid
61
CHF
CHF 61.00
In stock
CDX-C0703-G0011 gCHF 61.00
CDX-C0703-G0055 gCHF 204.00
| Product Details | |
|---|---|
| Synonyms | CGA; 3-CQA; 1,3,4,5-Tetrahydroxycyclohexanecarboxylic acid 3-(3,4-dihydroxycinnamate); 3-(3,4-Dihydroxycinnamoyl)quinic acid; 3-O-Caffeoylquinic Acid |
| Product Type | Chemical |
| Properties | |
| Formula | C16H18O9 |
| MW | 354.31 |
| CAS | 327-97-9 |
| RTECS | GU8480000 |
| Source/Host Chemicals | Isolated from plant source. |
| Purity Chemicals | ≥98% (HPLC) |
| Appearance | White to off-white powder. |
| Solubility | Soluble in ethanol, DMSO, DMF or PBS (pH 7.2) (all (25mg/ml). |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | CWVRJTMFETXNAD-BBVNJSSOSA-N |
| Smiles | O[C@]1(C(O)=O)CC(OC(/C=C/C2=CC=C(O)C(O)=C2)=O)[C@H](O)[C@@H](O)C1 |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +20°C |
| Long Term Storage | +4°C |
| Handling Advice | Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at +4°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
Chlorogenic acid is a phenolic natural product isolated from the leaves and fruits of dicotyledonous plants, including the coffee bean. Structurally, it is the ester of caffeic acid with the 3-hydroxyl group of quinic acid. Chlorogenic acid is an intermediate in lignin biosynthesisis an therefore an important factor in plant metabolism. This compound has been shown to have a broad range of biological properties, including hepatoprotective, antioxidant, neuroprotective, anti-diabetic, antimicrobial, anticarcinogenic, anti-inflammatory and anti-obesity activities. Recent studies showed the involvement in regulating glucose and lipid metabolism, improving insulin sensitivity and promotion of weight loss. In addition it has to have modulatory activities on the microbiota.
Product References
(1) M.T. Huang, et al.; Cancer Res. 48, 5941 (1988) | (2) M.T. Huang, et al.; Cancer Res. 51, 813 (1991) | (3) R. Feng, et al.; J. Biol. Chem. 280, 27888 (2005) | (4) M.D. dos Santos, et al.; Biol. Pharm. Bull. 29, 2236 (2006) | (5) W.J. Lee & B.T. Zhu; Carcinogenesis 27, 269 (2006) | (6) W.C. Chang, et al.; Eur. J. Nutr. 49, 267 (2010) | (7) S. Meng, et al.; Evid. Based Complement Alternat. Med. 2013, 801457 (2013) (Review) | (8) E. Heitman & D.K. Ingram; Nutr. Neurosci. 20, 32 (2017) (Review) | (9) J. Santana-Galvez, et al.; Molecules 22, E358 (2017) (Review) | (10) M. Naveed, et al.; Biomed. Pharmacother. 97, 67 (2018) (Review) | (11) X. Wang, et al.; J. Pharm. Pharmacol. 71, 1100 (2019) | (12) J.K. Kim & S.U. Park; EXCLI J. 18, 310 (2019) (Review)