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Chemodex
Cnidicin
122
CHF
CHF 122.00
In stock
CDX-C0728-M0011 mgCHF 122.00
| Product Details | |
|---|---|
| Synonyms | Kinidilin; Knidicin; 4,9-bis(3-methylbut-2-enoxy)furo[3,2-g]chromen-7-one |
| Product Type | Chemical |
| Properties | |
| Formula |
C21H22O5 |
| MW | 354.4 |
| CAS | 14348-21-1 |
| Source/Host Chemicals | Isolated from plant source. |
| Purity Chemicals | ≥98% (HPLC) |
| Appearance | Light yellow powder. |
| Solubility | Soluble in DMSO. |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | HJMDOAWWVCOEDW-UHFFFAOYSA-N |
| Smiles | C/C(C)=C/COC1=C2C(OC(C=C2)=O)=C(OC/C=C(C)/C)C3=C1C=CO3 |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
Cnidicin is a natural product isolated from the root extract of Angelica koreana (Umbelliferae). Cnidicin has anti-allergic and anti-inflammatory activity. It inhibits the degranulation of mast cell and the nitric oxide (NO) generation in RAW 264.7 cells, by inhibition of nitric oxide synthase expression. Cnidicin has shown anti-proliferative and cytotoxic activity in vitro on cultured human tumor cells such as A549 (non small cell lung), SK-OV-3 (ovary), SK-MEL-2 (melanoma), XF498 (central nervous system) and HCT-15 (colon).
Product References
(1) S.Y. Ryu, et al.; Planta Med. 67, 172 (2001) | (2) Y.K. Kim, et al.; Phytother. Res. 21, 288 (2007)