Cookie Policy: This site uses cookies to improve your experience. You can find out more about our use of cookies in our Privacy Policy. By continuing to browse this site you agree to our use of cookies.
Chemodex
Cholestyramine Resin
CHF 0.00
Out of stock
NEW
| Product Details | |
|---|---|
| Synonyms | Colestyramine; Quantalan; Cholybar; MK 135; Cholestyramine hydroxide |
| Product Type | Chemical |
| Properties | |
| Formula | n/a |
| MW | n/a |
| CAS | 11041-12-6 |
| Source/Host Chemicals | Synthetic |
| Appearance | White to yellow powder. |
| Solubility | Insoluble in water. Prepare aqueous suspensions. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | KLRGGCLCZSQPPH-UHFFFAOYSA-M |
| Smiles | C[N+](C)(CC1=CC=C(C(CC(CC)C2=CC=CC=C2)CC)C=C1)C.CCC(C)C.[Cl-] |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +20°C |
| Long Term Storage | +4°C |
| Handling Advice | Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at +4°C. |
| Documents | |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
Cholestyramine resin is a anion-exchange resin polymer. This resin is a bile acid sequestrant that interchanges chloride anions for bile acids of the small intestine lumen, leading to excretion of bile acids in the feces and reduced levels of serum bile acid. The resin induces dose-dependent reduction of low-density lipid (LDL) cholesterol. In laboratory research, cholestyramine resin serves as a versatile tool for the removal of bile salts, free fatty acids, endotoxins, and other anionic contaminants from biological samples or culture media. Its robust binding properties also make it useful for studying lipid metabolism, drug absorption, and detoxification processes. Cholestyramine resin is used in protein chromatography, ion exchange chromatography and anion exchange media.
Product References
(1) H.R. Casdorph; Calif. Med. 106, 293 (1967) | (1) W.G. Thompson & G.R. Thompson; Gut 10, 717 (1969) | (1) K.W. Heaton, et al.; Scand. J. Gastroenterol. 6, 281 (1971) | (1) W.G. Thompson; Can. Med. Assoc. J. 104, 305 (1971) | (1) W. Addleman; N. Engl. J. Med. 287, 1047 (1972) | (1) F. Scaldaferri, et al.; Intern. Emerg. Med. 8, 205 (2013)