Cookie Policy: This site uses cookies to improve your experience. You can find out more about our use of cookies in our Privacy Policy. By continuing to browse this site you agree to our use of cookies.
Chemodex
trans-4,5-Dihydroxy-1,2-dithiane
68
CHF
CHF 68.00
In stock
CDX-D0277-G0011 gCHF 68.00
CDX-D0277-G0055 gCHF 224.00
CDX-D0277-G100100 gCHF 2'374.00
| Product Details | |
|---|---|
| Synonyms | trans-1,2-Dithiane-4,5-diol; Cyclo-DTT; NSC 663605; Oxidized DTT |
| Product Type | Chemical |
| Properties | |
| Formula |
C4H8O2S2 |
| MW | 152.24 |
| CAS | 14193-38-5 |
| Source/Host Chemicals | Synthetic |
| Purity Chemicals | ≥97% (NMR) |
| Appearance | White to off-white powder. |
| Solubility | Soluble in DMSO or ethanol (20mg/ml). |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | YPGMOWHXEQDBBV-QWWZWVQMSA-N |
| Smiles | O[C@@H]1CSSC[C@H]1O |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | +4°C |
| Handling Advice | Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at +4°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
trans-4,5-Dihydroxy-1,2-dithiane (oxidized dtt) is an intramolecular disulfide form of dithiothreitol. Oxidized DTT exhibits a strong absorbance peak at 280 nm. It is a strong reducing agent with an ability to elicit a molecular stress response by activating the stress-responsive genes.
Product References
(1) D. Busse, et al.; Metabolism 36, 110 (1987) | (2) M.M. Halleck, et al.; J. Biol. Chem. 272, 21760 (1997) | (3) S. Asmellash, et al.; Toxicol. Sci. 88, 576 (2005)