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Chemodex
2,5-Dioxopyrrolidin-1-yl propanoate
Product Details | |
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Synonyms | N-(Propionyloxy)succinimide; N-succinimidyl propionate; NSP; Propionyl-Osu; 1-(1-Oxopropoxy)-2,5-pyrrolidinedione |
Product Type | Chemical |
Properties | |
Formula |
C7H9NO4 |
MW | 171.15 |
CAS | 30364-55-7 |
Source/Host Chemicals | Synthetic. |
Purity Chemicals | ≥95% (NMR) |
Appearance | White to off-white powder. |
Solubility | Soluble in chloroform. |
Identity | Determined by 1H-NMR. |
Declaration | Manufactured by Chemodex. |
Other Product Data |
Click here for Original Manufacturer Product Datasheet |
InChi Key | AASBXERNXVFUEJ-UHFFFAOYSA-N |
Smiles | CCC(ON1C(CCC1=O)=O)=O |
Shipping and Handling | |
Shipping | AMBIENT |
Short Term Storage | +20°C |
Long Term Storage | +4°C |
Handling Advice | Protect from light and moisture. |
Use/Stability | Stable for at least 2 years after receipt when stored at +4°C. |
Documents | |
MSDS | Download PDF |
Product Specification Sheet | |
Datasheet | Download PDF |
Biochemical for proteomics research use. Amine-specific protein-acylating agent. Used for derivatization of biogenic amines for hplc analysis. Recent stuides use this agent for derivatization of histone post-translational modifications. The compound has been used in several studies describing this well established reagent for the introduction of a tritium label into proteins or other biologicals. The retrograde transport of protein components of sciatic nerve axons has been demonstrated by direct labelling of the protein using [3H]NSP in vivo.
(1) J.C. Hedreen & G.C. Holm; Brain Res. Bull. 7, 665 (1981) | (2) Y.S. Tang; J. Labelled Comp. Radiopharm. 20, 277 (1982) | (3) U. Kummer; Meth. Enzymol. 121, 670 (1986) | (4) R. Liao, et al.; Anal. Chem. 85, 2253 (2013) | (5) J.Chen, et al.; Anal. Chim. Acta 886, 107 (2015)