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Chemodex
D-chiro-Inositol
Product Details | |
---|---|
Synonyms | DCI; 1,2,4/3,5,6-Hexahydroxycyclohexane; D-(+)-chiro-Inositol |
Product Type | Chemical |
Properties | |
Formula |
C6H12O6 |
MW | 180.16 |
CAS | 643-12-9 |
Purity Chemicals | ≥95% (HPLC) |
Appearance | White to off-white solid. |
Solubility | Soluble in water. |
Identity | Determined by 1H-NMR. |
Declaration | Manufactured by Chemodex. |
Other Product Data |
Click here for Original Manufacturer Product Datasheet |
InChi Key | CDAISMWEOUEBRE-LKPKBOIGSA-N |
Smiles | O[C@H]1[C@@H](O)[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O |
Shipping and Handling | |
Shipping | AMBIENT |
Short Term Storage | +4°C |
Long Term Storage | +4°C |
Handling Advice | Protect from light and moisture. |
Use/Stability | Stable for at least 2 years after receipt when stored at +4°C. |
Documents | |
MSDS | Inquire |
Product Specification Sheet | |
Datasheet | Download PDF |
D-chiro Inositol is a insulin sensitizing agent. It is a secondary messenger in the signal transduction of insulin. D-chiro Inositol reduces the effects of polycystic ovary syndrome (PCOS) activity in cells. D-chiro Inositol is a mediator of insulin action via accelerating the dephosphorylation of glycogen synthase and pyruvate dehydrogenase and rate limiting enzymes of non-oxidative and oxidative glucose disposal. As a result of these actions D-chiro Inositol functions to reduce insulin resistance and increase sensitivity and glucose disposal. Can also be used as a building block for organic synthesis.
(1) J. Larner; IUBMB Life 51, 139 (2001) (Review) | (2) J. Larner; Int. J. Exp. Diabetes Res. 3 47 (2002) | (3) J. Larner, et al.; Mol. Med. 16, 543 (2010) (Review) | (4) N. Galazis, et al.; Gynecol. Endocrinol. 27, 256 (2011) (Review) | (5) G.G. Adams, et al.; Crit. Rev. Food. Sci. Nutr. 54, 1322 (2014) (Review)