Chemodex

3,3'-Dimethyloxacarbocyanine iodide

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Product Details
Synonyms DiOC1(3); NK 86; DMOCI; 3,3'-Dimethyl-2,2'-oxacarbocyanine iodide
Product Type Chemical
Properties
Formula C19H17N2O2 . I
MW 432.26
CAS 14134-79-3
Source/Host Chemicals Synthetic
Purity Chemicals ≥99% (HPLC)
Appearance Orange to red powder.
Solubility Soluble in DMSO or ethanol.
Identity Determined by 1H-NMR.
Declaration Manufactured by Chemodex.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturer's product datasheet.

InChi Key PXGXZGVGEDLSMW-UHFFFAOYSA-M
Smiles C[N+]=1C=2C(OC1C=CC=C3N(C)C=4C(O3)=CC=CC4)=CC=CC2.[I-]
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Keep under inert gas.
Protect from light and oxygen.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
Product Specification Sheet
Datasheet Download PDF
Description
DiOC1(3) is a fluorescent carbocyanine dye used to measure mitochondrial membrane potential or staining of plasma membranes or nucleic acid (DNA). It can be used for flow cytometry and fluorescent microscopy and for discrimination of viable cells. Also used for imaging of fixed cells. Used as a donor in TR-FRET. Spectral Data: Excitation max: ~ 488nm, Emission max: ~500-530nm (accord. Lit). Intermediate for the synthesis of fluorescent probes.
Product References
(1) W. West, et al.; J. Phys. Chem. 71, 1316 (1967) | (2) J.S. Huebner; J. Membr. Biol. 39, 97 (1978) | (3) J.S. Huebner & W.E. Varnadore; Photochem. Photobiol. 35, 141 (1982) | (4) D.H. Wiegand & P. Vanysek; Appl. Spectrosc. 42, 958 (1988) | (5) J.C. Stockert; Acta Histochem. 102, 259 (2000) | (6) U. Tripathy, et al.; Chem. Phys. 299, 105 (2004) | (7) J.C. Stockert, et al.; Acta Histochem. 106, 413 (2005) | (8) U. Tripathy, et al.; Res. Chem. Intermed. 31, 649 (2005) | (9) U. Tripathy & P.B. Bisht; J. Chem. Phys. 125, 144502 (2006)
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