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Chemodex
Daidzin
34
CHF
CHF 34.00
In stock
CDX-D0926-M0055 mgCHF 34.00
CDX-D0926-M02525 mgCHF 135.00
| Product Details | |
|---|---|
| Synonyms | Daidzein-7-O-β-D-glucopyranoside; Daidzoside; NPI 031D; BRN 0059741 |
| Product Type | Chemical |
| Properties | |
| Formula |
C21H20O9 |
| MW | 416.38 |
| CAS | 552-66-9 |
| RTECS | DJ3094000 |
| Source/Host Chemicals | Plant |
| Purity Chemicals | ≥98% (HPLC) |
| Appearance | White powder. |
| Solubility | Soluble in DMSO (20mg/ml), DMF (20mg/ml) or ethanol (2mg/ml). |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | KYQZWONCHDNPDP-QNDFHXLGSA-N |
| Smiles | O=C1C(C2=CC=C(O)C=C2)=COC3=CC(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)=CC=C31 |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +20°C |
| Long Term Storage | +4°C |
| Handling Advice | Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at +4°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
Daidzin is a naturally occuring isoflavone. It is the major active component of the traditional Chinese medicine (TCM) derived from radix puerariae (Kudzu) that is commonly used to treat alcohol abuse. Like other isoflavones, daidzin has anti-oxidant, anti-carcinogenic and anti-atherosclerotic activities. Daidzin directly inhibits mitochondrial aldehyde dehydrogenase 2 (ALDH-2) (IC50=80nM) and is an effective anti-dipsotropic isoflavone.
Product References
(1) W.M. Keung & B.L. Vallee; PNAS 90, 1247 (1993) | (2) C.I. Xie, et al.; Alcohol Clin. Exp. Res. 18, 1443 (1994) | (3) W.M. Keung & B.L. Vallee; PNAS 95, 2198 (1998) | (4) K. Kato, et al.; Jpn. J. Cancer Res. 91, 786 (2000) | (5) X.H. Li, et al.; Acta Pharmacol. Sin. 26, 1081 (2005) | (6) E.D. Lowe, et al.; J. Med. Chem. 51, 4482 (2008) | (7) Y. Zang, et al.; Biosci. Biotechnol. Biochem. 79, 117 (2015) | (8) G. Wei, et al.; J. Cell Biochem. 120, 5304 (2019)