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Chemodex
1,1'-Didodecyl-3,3,3',3'-tetramethyl indocarbocyanine perchlorate
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161
CHF
CHF 161.00
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CDX-D1022-M05050 mgCHF 161.00
CDX-D1022-M100100 mgCHF 271.00
CDX-D1022-M250250 mgCHF 561.00
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Product Details | |
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Synonyms | DiIC12(3) |
Product Type | Chemical |
Properties | |
Formula | C47H73N2 . ClO4 |
MW | 765.55 |
CAS | 84109-08-0 |
Source/Host Chemicals | Synthetic |
Purity Chemicals | ≥99% (HPLC) |
Appearance | Dark green-yellow solid or chunks. |
Solubility | Soluble in DMSO or methanol. |
Identity | Determined by 1H-NMR. |
Declaration | Manufactured by Chemodex. |
Other Product Data |
Click here for Original Manufacturer Product Datasheet |
InChi Key | MPVFAUXPXHGRPQ-UHFFFAOYSA-M |
Smiles | CCCCCCCCCCCCN1C2=CC=CC=C2C(C1=CC=CC3=[N+](C4=CC=CC=C4C3(C)C)CCCCCCCCCCCC)(C)C.[O-]Cl(=O)(=O)=O |
Shipping and Handling | |
Shipping | AMBIENT |
Short Term Storage | +4°C |
Long Term Storage | -20°C |
Handling Advice |
Keep under inert gas. Protect from light and oxygen. |
Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
Documents | |
Product Specification Sheet | |
Datasheet |
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Description
DiIC12(3) is a lipophilic fluorescent carbocyanine dye used to measure mitochondrial membrane potential. Can be used for neuronal tracing, vascular imaging and cell membrane labeling. It may incorporate into membranes more easily than DiI. It is weakly fluorescent in water but highly fluorescent and quite photostable when incorporated into membranes. It has an extremely high extinction coefficient and short excited-state lifetimes (~1 nanosecond) in lipid environments. Once applied to cells, the dye diffuses laterally within the plasma membrane. Spectral Data: Excitation max: ~ 549nm, Emission max: ~564nm (MeOH).
Product References
(1) P.A. St John; Life Sci. 49, 2013 (1991) | (2) L.S. De Clerck, et al.; J. Immunol. Meth. 172, 115 (1994) | (3) S. Mukherjee, et al.; J. Cell Biol. 144, 1271 (1999) | (4) L.M. Loura, et al.; Biochim. Biophys. Acta 1467, 101 (2000) | (5) M.J. Wirth, et al.; J. Chromatogr. A. 1034, 69 (2004) | (6) A.F. Na, et al.; J. Pediatr. Surg. 42, 1566 (2007) | (7) E. Braeken, et al.; Chem. Phys. Lett. 472, 48 (2009) | (8) J.J. Strouse, et al.; Anal. Biochem. 437, 77 (2013)