Chemodex

1,1'-Didodecyl-3,3,3',3'-tetramethyl indocarbocyanine perchlorate

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CDX-D1022-M05050 mgCHF 161.00
CDX-D1022-M100100 mgCHF 271.00
CDX-D1022-M250250 mgCHF 561.00
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Product Details
Synonyms DiIC12(3)
Product Type Chemical
Properties
Formula C47H73N2 . ClO4
MW 765.55
CAS 84109-08-0
Source/Host Chemicals Synthetic
Purity Chemicals ≥99% (HPLC)
Appearance Dark green-yellow solid or chunks.
Solubility Soluble in DMSO or methanol.
Identity Determined by 1H-NMR.
Declaration Manufactured by Chemodex.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturer's product datasheet.

InChi Key MPVFAUXPXHGRPQ-UHFFFAOYSA-M
Smiles CCCCCCCCCCCCN1C2=CC=CC=C2C(C1=CC=CC3=[N+](C4=CC=CC=C4C3(C)C)CCCCCCCCCCCC)(C)C.[O-]Cl(=O)(=O)=O
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Keep under inert gas.
Protect from light and oxygen.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
Product Specification Sheet
Datasheet Download PDF
Description
DiIC12(3) is a lipophilic fluorescent carbocyanine dye used to measure mitochondrial membrane potential. Can be used for neuronal tracing, vascular imaging and cell membrane labeling. It may incorporate into membranes more easily than DiI. It is weakly fluorescent in water but highly fluorescent and quite photostable when incorporated into membranes. It has an extremely high extinction coefficient and short excited-state lifetimes (~1 nanosecond) in lipid environments. Once applied to cells, the dye diffuses laterally within the plasma membrane. Spectral Data: Excitation max: ~ 549nm, Emission max: ~564nm (MeOH).
Product References
(1) P.A. St John; Life Sci. 49, 2013 (1991) | (2) L.S. De Clerck, et al.; J. Immunol. Meth. 172, 115 (1994) | (3) S. Mukherjee, et al.; J. Cell Biol. 144, 1271 (1999) | (4) L.M. Loura, et al.; Biochim. Biophys. Acta 1467, 101 (2000) | (5) M.J. Wirth, et al.; J. Chromatogr. A. 1034, 69 (2004) | (6) A.F. Na, et al.; J. Pediatr. Surg. 42, 1566 (2007) | (7) E. Braeken, et al.; Chem. Phys. Lett. 472, 48 (2009) | (8) J.J. Strouse, et al.; Anal. Biochem. 437, 77 (2013)
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