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Chemodex
N-Ethanoyl-L-homoserine lactone
95
CHF
CHF 95.00
In stock
CDX-E0072-M0055 mgCHF 95.00
CDX-E0072-M02525 mgCHF 285.00
Product Details | |
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Synonyms | C2-HSL; N-Acetyl-L-homoserine lactone; N-[(3S)-Tetrahydro-2-oxo-3-furanyl]-acetamide |
Product Type | Chemical |
Properties | |
Formula | C6H9NO3 |
MW | 143.14 |
CAS | 51524-71-1 |
Source/Host Chemicals | Synthetic |
Purity Chemicals | ≥98% (GC) |
Appearance | White powder. |
Solubility | Soluble in ethanol, methanol, DMF or DMSO. Poorly soluble in water. |
Identity | Determined by NMR. |
Declaration | Manufactured by Chemodex. |
Other Product Data |
Click here for Original Manufacturer Product Datasheet |
InChi Key | XGSXMDQVYYCSDA-YFKPBYRVSA-N |
Smiles | CC(=O)N[C@H]1CCOC1=O |
Shipping and Handling | |
Shipping | AMBIENT |
Short Term Storage | +4°C |
Long Term Storage | -20°C |
Handling Advice |
Keep cool and dry. Protect from light and moisture. |
Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
Documents | |
MSDS | Inquire |
Product Specification Sheet | |
Datasheet | Download PDF |
Description
N-Ethanoyl-L-homoserine lactone is the shortest alkyl homologue and most polar of a family of mediators of cell to cell interactions in bacterial biofilms. Acylhomoserine lactones have been detected in hundreds of bacterial species. N-acylhomoserine lactones (AHL) are involved in quorum sensing, controlling gene expression, and cellular metabolism. N-Ethanoyl-L-homoserine lactone is not found in nature and can serve as a polar negative control for quorum sensing events.
Product References
(1) K.H. McClean, et al.; Microbiol. 143, 3703 (1997) | (2) A. Kumari, et al.; Anal. Chem. 78, 7603 (2006)
- Human TRPV1 and TRPA1 are receptors for bacterial quorum sensing molecules: N. Tobita, et al.; J. Biochem. ahead of print (2021)