N-Ethanoyl-L-homoserine lactone

CHF 95.00
In stock
CDX-E0072-M0055 mgCHF 95.00
CDX-E0072-M02525 mgCHF 285.00
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Product Details
Synonyms C2-HSL; N-Acetyl-L-homoserine lactone; N-[(3S)-Tetrahydro-2-oxo-3-furanyl]-acetamide
Product Type Chemical
Formula C6H9NO3
MW 143.14
CAS 51524-71-1
Source/Host Chemicals Synthetic
Purity Chemicals ≥98% (GC)
Appearance White powder.
Solubility Soluble in ethanol, methanol, DMF or DMSO. Poorly soluble in water.
Identity Determined by NMR.
Declaration Manufactured by Chemodex.
Other Product Data

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Smiles CC(=O)N[C@H]1CCOC1=O
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Keep cool and dry.
Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
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Product Specification Sheet
Datasheet Download PDF

N-Ethanoyl-L-homoserine lactone is the shortest alkyl homologue and most polar of a family of mediators of cell to cell interactions in bacterial biofilms. Acylhomoserine lactones have been detected in hundreds of bacterial species. N-acylhomoserine lactones (AHL) are involved in quorum sensing, controlling gene expression, and cellular metabolism. N-Ethanoyl-L-homoserine lactone is not found in nature and can serve as a polar negative control for quorum sensing events.

Product References

(1) K.H. McClean, et al.; Microbiol. 143, 3703 (1997) | (2) A. Kumari, et al.; Anal. Chem. 78, 7603 (2006)

  1. Human TRPV1 and TRPA1 are receptors for bacterial quorum sensing molecules: N. Tobita, et al.; J. Biochem. ahead of print (2021)
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