(-)-Epicatechin gallate

Specifications / Handling

More Information
Product Details
Synonyms	ECG; (-)-cis-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol 3-gallate
Product Type	Chemical
Properties
Formula	C₂₂H₁₈O₁₀
MW	442.37
CAS	1257-08-5
RTECS	DH9030000
Source/Host Chemicals	Isolated from plant source.
Purity Chemicals	≥98% (HPLC)
Appearance	Light-yellow powder.
Solubility	Soluble in water, acetone, DMSO (10mg/ml), methanol, ethanol (1mg/ml) or DMF (10mg/ml).
Identity	Determined by ¹H-NMR.
Declaration	Manufactured by Chemodex.
Other Product Data	Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet.
InChi Key	LSHVYAFMTMFKBA-TZIWHRDSSA-N
Smiles	OC1=C(C[C@@H](OC(C2=CC(O)=C(O)C(O)=C2)=O)[C@@H](C3=CC=C(O)C(O)=C3)O4)C4=CC(O)=C1
Shipping and Handling
Shipping	AMBIENT
Short Term Storage	+20°C
Long Term Storage	+4°C
Handling Advice	Protect from light and moisture.
Use/Stability	Stable for at least 2 years after receipt when stored at +4°C.
Documents
MSDS	Download PDF
Product Specification Sheet
Datasheet	Download PDF

Product-specific References

Description

The catechins (-)-epicatechin (EC) and (-)-epigallocatechin gallate (EGCG) are abundant in green and black teas. (-)-Epicatechin gallate (ECG) is a natural catechin with a single galloyl group. Like EGCG, it inhibits the growth of cancer cells and has anti-inflammatory effects. The hydroxyl groups of ECG contribute to its potent antioxidant activity and facilitate the killing of methicillin-resistant strains of S. aureus.

Product References

(1) J.Z. Xu, et al.; Br. J. Nutr. 91, 873 (2004) | (2) M.H. Ravindranath, et al.; Evidence-Based Compl. Altern. Med. 6, 523 (2009) | (3) C. Kuerbitz, et al.; Cancer Sci. 102, 728 (2011) | (4) J.C. Anderson, et al.; Bioorg. Med. Chem. Lett. 21, 6996 (2011) | (5) G.J. Du, et al.; Nutrients 4, 1679 (2012)

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