Glucuronolactone

CHF 57.00
In stock
CDX-G0044-G02525 gCHF 57.00
CDX-G0044-G250250 gCHF 153.00
CDX-G0044-G500500 gCHF 281.00
More Information
Product Details
Synonyms D-(+)-Glucuronic acid γ-lactone; D-(+)-Glucurono-6,3-lactone; D-Glucurono-6,3-lactone; D-Glucurone
Product Type Chemical
Properties
Formula C6H8O6
MW 176.12
CAS 32449-92-6
Purity Chemicals ≥98% (HPLC)
Appearance White powder.
Solubility Soluble in water.
Identity Determined by NMR.
Declaration Manufactured by Chemodex.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

InChi Key OGLCQHRZUSEXNB-VGASXLIASA-N
Smiles O[C@@H]1[C@@H](OC2=O)[C@@H]([C@@H]2O)OC1O
Shipping and Handling
Shipping AMBIENT
Short Term Storage +20°C
Long Term Storage +20°C
Handling Advice Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at +20°C.
Documents
MSDS Inquire
Product Specification Sheet
Datasheet Download PDF

Naturally occurring carbohydrate derivative that is an important structural component of nearly all connective tissues and is also found in many plant gums. Metabolized to glucaric acid, xylitol, and L-xylulose, and humans may also be able to use glucuronolactone as a precursor for ascorbic acid synthesis. Used as a detoxicant. The liver uses glucose to create glucuronolactone, which inhibits the enzyme B-glucuronidase (metabolizes glucuronides), which should cause blood-glucuronide levels to rise. Glucuronides combine with toxic substances, such as morphine and depot medroxyprogesterone acetate, by converting them to water-soluble glucuronide-conjugates which are excreted in the urine. Used as building block and starting reagent for synthesis of drugs, optically active glucopyranoses and long-chain alkyl glucofuranosides.

Product References

(1) C.A. Marsh; Biochem. J. 99, 22 (1966) | (2) S.H. Kim, et al.; Acta Crystallogr. 22, 733 (1967) | (3) L. Trahan, et al.; Rev. Can. Biol. 29, 7 (1970) | (4) T. Kuzuya, et al.; Endocrinol. Jpn. 20, 369 (1973) | (5) A. Kirschning, et al.; Bioorg. Med. Chem. Lett. 7, 903 (1997) | (6) S. Suzuki, et al.; J. Chromatogr. Sci. 36, 357 (1998) | (7) A.F. Glawar, et al.; Chemistry 18, 9341 (2012)

© 2017 Adipogen Life Sciences. Pictures: © 2012 Martin Oeggerli. All Rights Reserved.