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Chemodex
Glycitin
Product Details | |
---|---|
Synonyms | 7-(β-D-Glucopyranosyloxy)-3-(4-hydroxyphenyl)-6-methoxy-4H-1-benzopyran-4-one; Glycitein-7-β-O-glucoside |
Product Type | Chemical |
Properties | |
Formula |
C22H22O10 |
MW | 446.4 |
CAS | 40246-10-4 |
Source/Host Chemicals | Plant |
Purity Chemicals | ≥98% (HPLC) |
Appearance | White powder. |
Solubility | Soluble in DMSO (20mg/ml) or DMF (20mg/ml). |
Identity | Determined by 1H-NMR. |
Declaration | Manufactured by Chemodex. |
Other Product Data |
Click here for Original Manufacturer Product Datasheet |
InChi Key | OZBAVEKZGSOMOJ-MIUGBVLSSA-N |
Smiles | OC(C=C1)=CC=C1C2=COC3=CC(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)=C(OC)C=C3C2=O |
Shipping and Handling | |
Shipping | AMBIENT |
Short Term Storage | +20°C |
Long Term Storage | +20°C |
Handling Advice | Protect from light and moisture. |
Use/Stability | Stable for at least 2 years after receipt when stored at RT. |
Documents | |
MSDS | Inquire |
Product Specification Sheet | |
Datasheet | Download PDF |
Glycitin is a natural isoflavone isolated from legumes, including soy and kudzu. It has been reported to have multiply biological functions, such as anti-inflammatory, antioxidant, antiobesity, anticardiovascular activity and promoting wound healing. Like other isoflavones, glycitin promotes the proliferation of bone marrow stromal cells and osteoblasts and suppresses bone turnover. Glycitin can be modified by the action of beta-glucosidases into the metabolite glycitein which has anti-inflammatory properties.
(1) T. Uesugi, et al.; Biol. Pharm. Bull. 24, 368 (2001) | (2) X.H. Li, et al.; Acta Pharmacol. Sin. 26, 1081 (2005) | (3) Y. Zang, et al.; Biosci. Biotechnol. Biochem. 79, 117 (2015) | (4) Y.M. Kim, et al.; Phytother. Res. 29, 757 (2015) | (5) L. Zhang, et al.; Exp. Ther. Med. 12, 3063 (2016) | (6) G.Y. Seo, et al.; Exp. Mol. Med. 49, e302 (2017) | (7) Y. Chen, et al.; Int. Immunopharmacol. 75, 105749 (2019)