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Chemodex
7-Hydroxy-4-coumarinylacetic acid
95
CHF
CHF 95.00
In stock
CDX-H0008-G0055 gCHF 95.00
| Product Details | |
|---|---|
| Synonyms | 7-HCA; 7-Hydroxycoumarin-4-acetic acid; Umbelliferone-4-acetic acid; NSC 642907; NSC 65625 |
| Product Type | Chemical |
| Properties | |
| Formula |
C11H8O5 |
| MW | 220.18 |
| CAS | 6950-82-9 |
| Source/Host Chemicals | Plant |
| Purity Chemicals | ≥98% (NMR) |
| Appearance | Beige powder. |
| Solubility | Soluble in DMSO or methanol. |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | BNHPMQBVNXMPDU-UHFFFAOYSA-N |
| Smiles | OC1=CC=C2C(OC(C=C2CC(O)=O)=O)=C1 |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
7-Hydroxycoumarin-4-acetic acid is a fluorescent pH indicator. 7-Hydroxycoumarin-4-acetic acid is used for labeling amine-specific peptides, proteins and other biological molecules to give blue fluorescence. It is used as fluorigenic substrate, e.g. in BSA-HCA complexes for fatty acid concentration measurement or for fluorometric enzymatic analysis. It also can be used as a building block for synthesis of other coumarin-based probes. Spectral data: λEx=360nm; λEm=450nm (DMSO).
Product References
(1) G. Gabor & D.R. Walt; Anal. Chem. 63, 793 (1991) | (2) E.J.F. Demant; BBA 1304, 43 (1996) | (3) J.F. Sierra, et al.; Anal. Chim. Acta 368, 97 (1998) | (4) E.J.F. Demant; Anal. Biochem. 267, 366 (1999) | (5) C. Charitos, et al.; J. Heterocyclic Chem. 38, 153 (2001) | (6) K.F. Chilvers, et al.; J. Appl. Microbiol. 91, 1118 (2001) | (7) S. Chen, et al.; Anal. Meth. 7, 7646 (2015) | (8) L. Rong, et al.; Chem. Commun. 50, 667 (2014)