Resorufin-isobutyrate

CHF 100.00
In stock
CDX-I0005-M0011 mgCHF 100.00
CDX-I0005-M0055 mgCHF 268.00
CDX-I0005-M02525 mgCHF 1'068.00
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Product Details
Synonyms 7-(Isobutyloxycarbonyloxy)-3H-phenoxazin-3-one; CytoRed
Product Type Chemical
Properties
Formula C17H15NO5
MW 313.3
CAS 251292-24-7
Source/Host Chemicals Synthetic.
Purity Chemicals ≥97% (HPLC)
Appearance Solid.
Solubility Soluble in DMSO.
Identity Determined by 1H-NMR.
Declaration Manufactured by Chemodex.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

InChi Key RVDFSVVDUVHHKE-UHFFFAOYSA-N
Smiles CC(C)COC(=O)OC1=CC2=C(C=C1)N=C1C=CC(=O)C=C1O2
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
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Product Specification Sheet
Datasheet Download PDF

Cell permeable resorufin derivative used as a fluorogenic indicator for cell viability. Resorufin was selected as the fluorophore because it fluoresces at a longer wavelength and is amenable to modification at the hydroxyl group which is essential for its fluorescence. Incubation with esterase at pH 8.0 results in a 80-90 nm shift of emission max. (Ex/Em: 500/~593nm in 0.1 M Tris pH 8.0 (after cleavage by esterase)). This cell viability indicator is 2 times more sensitive than calcein-AM.

Product References

(1) M. Ishiyama et al.; Analyt. Sci. 15, 1025 (1999)

Multiplexing fluorogenic esterase-based viability assay with luciferase assays: K. Ohgane, et al. MethodsX 6, 2013 (2019)

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