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Chemodex
Resorufin-isobutyrate
106
CHF
CHF 106.00
In stock
CDX-I0005-M0011 mgCHF 106.00
CDX-I0005-M0055 mgCHF 285.00
CDX-I0005-M02525 mgCHF 1'136.00
Product Details | |
---|---|
Synonyms | 7-(Isobutyloxycarbonyloxy)-3H-phenoxazin-3-one; CytoRed |
Product Type | Chemical |
Properties | |
Formula | C17H15NO5 |
MW | 313.3 |
CAS | 251292-24-7 |
Source/Host Chemicals | Synthetic. |
Purity Chemicals | ≥97% (HPLC) |
Appearance | Solid. |
Solubility | Soluble in DMSO. |
Identity | Determined by 1H-NMR. |
Declaration | Manufactured by Chemodex. |
Other Product Data |
Click here for Original Manufacturer Product Datasheet |
InChi Key | RVDFSVVDUVHHKE-UHFFFAOYSA-N |
Smiles | CC(C)COC(=O)OC1=CC2=C(C=C1)N=C1C=CC(=O)C=C1O2 |
Shipping and Handling | |
Shipping | AMBIENT |
Short Term Storage | +4°C |
Long Term Storage | -20°C |
Handling Advice | Protect from light and moisture. |
Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
Documents | |
MSDS | Inquire |
Product Specification Sheet | |
Datasheet | Download PDF |
Description
Cell permeable resorufin derivative used as a fluorogenic indicator for cell viability. Resorufin was selected as the fluorophore because it fluoresces at a longer wavelength and is amenable to modification at the hydroxyl group which is essential for its fluorescence. Incubation with esterase at pH 8.0 results in a 80-90 nm shift of emission max. (Ex/Em: 500/~593nm in 0.1 M Tris pH 8.0 (after cleavage by esterase)). This cell viability indicator is 2 times more sensitive than calcein-AM.
Product References
(1) M. Ishiyama et al.; Analyt. Sci. 15, 1025 (1999) | (2) K. Ohgane, et al. MethodsX 6, 2013 (2019)