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Chemodex
Isoorientin
54
CHF
CHF 54.00
In stock
CDX-I0095-M0011 mgCHF 54.00
CDX-I0095-M0055 mgCHF 102.00
CDX-I0095-M01010 mgCHF 183.00
| Product Details | |
|---|---|
| Synonyms | Homoorientin; Luteolin 6-C-β-D-glucoside; Luteolin 6-C-glucoside; Lespecapitioside |
| Product Type | Chemical |
| Properties | |
| Formula | C21H20O11 |
| MW | 448.38 |
| CAS | 4261-42-1 |
| RTECS | DJ3009250 |
| Source/Host Chemicals | Isolated from plant source. |
| Purity Chemicals | ≥98% (HPLC) |
| Appearance | Yellow powder. |
| Solubility | Soluble in DMSO (15mg/ml), DMF (15mg/ml) or methanol (5mg/ml). |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | ODBRNZZJSYPIDI-VJXVFPJBSA-N |
| Smiles | OC(C(C(C=C(C1=CC(O)=C(O)C=C1)O2)=O)=C2C=C3O)=C3[C@H]4[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O4 |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +20°C |
| Long Term Storage | +4°C |
| Handling Advice | Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at +4°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
Isoorientin is a flavonoid with various biological properties. It has anticancer, antioxidant, anti-inflammatory, antimicrobial, gastroprotective and antinociceptive activities. It induces apoptosis in and reduces cell viability of cancer cells. It is a selective Cyclooxygenase-2 (COX-2) inhibitor. Reduces expression of COX-2, IL-6, 5-lipoxygenase (5-LO), and TNF-α in RAW 264.7 cells. It also has shown to regulate lipid metabolism.
Product References
(1) M. Sumalatha, et al.; Nat. Prod. Commun. 10, 1703 (2015) | (2) L. Yuan, et al.; J. Agric. Food Chem. 64, 2682 (2016) | (3) X. Lin, et al.; J. Ethnopharmacol. 187, 187 (2016) | (4) L. Yuan, et al.; Biomed. Pharmacother. 81, 356 (2016) | (5) T. Ye, et al.; Onco. Targets Ther. 9, 7481 (2016) | (6) K. Anilkumar, et al.; Oxid. Med. Cell. Longev. 2017, 5498054 (2017) | (7) E.S. Karaoglan, et al.; Acta. Cir. Bras. 33, 609 (2018) | (8) L. Yuan, et al.; J. Agric. Food Chem. 66, 9777 (2018) | (9) G. Zhang, et al.; Int. Immunopharmacol. 75, 105753 (2019)