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Chemodex
Ketorolac trometamol
66
CHF
CHF 66.00
In stock
CDX-K0030-G0011 gCHF 66.00
CDX-K0030-G0055 gCHF 264.00
| Product Details | |
|---|---|
| Synonyms | (±)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid tris salt; Ketorolac tromethamine; Toradol; Ketorolac tris salt |
| Product Type | Chemical |
| Properties | |
| Formula |
C15H13NO3 . C4H11NO3 |
| MW | 376.4 |
| CAS | 74103-07-4 |
| RTECS | UY7759900 |
| Source/Host Chemicals | Synthetic. |
| Purity Chemicals | ≥99% (HPLC) |
| Appearance | White to off-white powder. |
| Solubility | Soluble in DMSO, DMF, water or methanol. |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | BWHLPLXXIDYSNW-UHFFFAOYSA-N |
| Smiles | O=C(C1=CC=CC=C1)C2=CC=C3N2CCC3C(O)=O.OCC(CO)(CO)N |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +20°C |
| Long Term Storage | +20°C |
| Handling Advice | Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at +4°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
Ketorolac is a non-steroidal anti-inflammatory drug (NSAID) to treat pain. It is a non-selective COX inhibitor (IC50 = 20nM for both COX-1 and COX-2), thereby decreasing prostaglandins. Ketorolac is a racemic mixture containing the active (S)-ketorolac and inactive (R)-ketorolac enantiomers. Formulations containing ketorolac have been used to manage postoperative pain and as ophthalmic solutions to treat ocular pain and inflammation.
Product References
(1) K.M. Litvak & G.K. McEvoy; Clin. Pharm. 9, 921 (1990) | (2) M.M. Buckley & R.N. Brogden; Drugs 39, 86 (1990) | (3) Y. Zhang, et al.; J. Pharmacol. Exp. Ther. 283, 1069 (1997) | (4) O. Laneuville, et al.; J. Pharmacol. Exp. Ther. 271, 927 (1994)