Latanoprost

Specifications / Handling

More Information
Product Details
Synonyms	Xalatan; Isopropyl (5Z,9a,11a,15R)-9,11,15-trihydroxy-17-phenyl-18,19,20-trinor-prost-5-en-1-oate; 17-phenyl-13,14-dihydro trinor Prostaglandin F2α isopropyl ester
Product Type	Chemical
Properties
Formula	C₂₆H₄₀O₅
MW	432.59
CAS	130209-82-4
RTECS	MJ9669550
Source/Host Chemicals	Synthetic
Purity Chemicals	≥98% (HPLC)
Appearance	Yellowish oily liquid.
Solubility	Soluble in DMSO, methanol or ethanol.
Identity	Determined by ¹H-NMR.
Declaration	Manufactured by Chemodex.
Other Product Data	Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet.
InChi Key	GGXICVAJURFBLW-CEYXHVGTSA-N
Smiles	O[C@@H]1[C@H](C/C=C\CCCC(OC(C)C)=O)[C@@H](CC[C@@H](O)CCC2=CC=CC=C2)[C@H](O)C1
Shipping and Handling
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	Protect from light and moisture.
Use/Stability	Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS	Inquire
Product Specification Sheet
Datasheet	Download PDF

Product-specific References

Description

Latanoprost is the isopropyl ester of 17-phenyl-13,14-dihydro prostaglandin F2α (17-phenyl-13,14-dihydro PGF2α). It is a prodrug form of the free acid, which is a potent agonist of the FP prostaglandin receptor in the eye. Latanoprost reduces intraocular pressure in glaucoma patients with few side effects.

Product References

(1) J. Stjernschantz & B. Resul; Drugs Future 17, 691 (1992) | (2) A. Alm, et al.; Ophthalmol. 100, 1312 (1993) | (3) C.B. Camras, et al.; Ophthalmol. 103, 1916 (1996) | (4) E. Linden, et al.; Br. J. Ophthalmol. 81, 370 (1997) | (5) J. Stjernschantz; Invest. Ophthalmol. Vis. Sci. 42, 1134 (2001) (Review) | (6) A. Alm, et al.; Clin Ophthalmol. 8, 1967 (2014) (Review)

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