2'-(4-Methylumbelliferyl)-α-D-N-acetylneuraminic acid sodium salt hydrate

CHF 51.00
In stock
CDX-M0096-M0011 mgCHF 51.00
CDX-M0096-M0055 mgCHF 204.00
CDX-M0096-M02525 mgCHF 715.00
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Product Details
Synonyms 4-MUNANA; 4-Methylumbelliferyl-N-acetyl-α-D-neuraminic acid sodium salt hydrate; Neu5Ac-α-4MU; 4MU-NeuNAc
Product Type Chemical
Properties
Formula C21H24NNaO11 . xH2O
MW 489.41 (anhydrous basis)
CAS 76204-02-9 (anhydrous)
Source/Host Chemicals Synthetic
Purity Chemicals ≥95% (NMR)
Appearance Light yellow powder.
Solubility Soluble in water or methanol.
Identity Determined by NMR.
Declaration Manufactured by Chemodex.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

InChi Key NSQMRVBWXQQIKF-HCNBQXOJSA-M
Smiles O.CC(=O)N[C@@H]1[C@H](O)C[C@@](OC2=CC3=C(C=C2)C(C)=CC(=O)O3)(OC1[C@H](O)[C@H](O)CO)C(=O)O[Na]
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Keep cool and dry.
Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS Inquire
Product Specification Sheet
Datasheet Download PDF

Fluorogenic substrate used to measure sensitively enzymatic neuraminidase activity in fluorometric assays in mammalian and viral sources. Neuraminidase is catalyzed by the hydrolysation to form N-acetylneuraminic acid and the blue fluorescent soluble compound 4-Methylumbelliferone, which can be detected fluorometrically. Spectral data: λex 315 nm| λem 374 nm (pH.7.0) or λex 365 nm| λem 445 nm (after cleavage by neuraminidase). Used for fluorescent staining of sialidases in PAGE.

Product References

(1) M. Potier, et al.; Anal. Biochem. 94, 287 (1979) | (2) R.W. Myers, et al.; Anal. Biochem. 101, 166 (1980) | (3) S. Matsuzaki, et al.; Jpn. J. Med. 23, 123 (1987) | (4) E. Monti, et al.; Glycobiol. 9, 1313 (1999) | (5) N.T. Wetherall, et al.; J. Clin. Microbiol. 41, 742 (2003) |(6) D.P. Nayak & U. Reichl; J. Virol. Meth. 122, 9 (2004) | (7) H.L. Yen, et al.; J. Virol. 80, 8787 (2006) | (8) H. Zhi, et al.; J. Spectrosc. 2013, 1 (2014)

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