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Chemodex
Midodrine hydrochloride
258
CHF
CHF 258.00
In stock
CDX-M0238-G0011 gCHF 258.00
| Product Details | |
|---|---|
| Synonyms | (±)-1-(2,5-Dimethoxyphenyl)-2-glycinamidoethanol |
| Product Type | Chemical |
| Properties | |
| Formula |
C12H18N2O4 . HCl |
| MW | 290.74 |
| CAS | 3092-17-9 |
| RTECS | AB4343000 |
| Purity Chemicals | ≥98% (HPLC) |
| Appearance | White to off-white powder. |
| Solubility | Soluble in DMSO (10mg/ml), DMF (2mg/ml) or water (0.5mg/ml). |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | MGCQZNBCJBRZDT-UHFFFAOYSA-N |
| Smiles | OC(CNC(CN)=O)C1=C(OC)C=CC(OC)=C1.Cl |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +20°C |
| Long Term Storage | +20°C |
| Handling Advice | Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at RT. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
Midodrine is a vasopressor/antihypotensive agent and a long acting α-adrenergic stimulating agent. Midodrine is a prodrug which forms an active metabolite, desglymidodrine, which is an α1-receptor agonist and exerts its actions via activation of the α-adrenergic receptors of the arteriolar and venous vasculature, producing an increase in vascular tone and elevation of blood pressure.
Product References
(1) H. Pittner; Naunyn Schmiedebergs Arch. Pharmacol. 287, R22 (1975) | (2) D. McTavish & K.L. Goa; Drugs 38, 757 (1989) (Review) | (3) D.N. Cruz; Expert Opin. Pharmacother. 1, 835 (2000) (Review)