Chemodex

2-Methoxy-2,4-diphenyl-3(2H)-furanone

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Product Details
Synonyms MDPF; 2,4-Diphenyl-2-methoxy-3(2H)-furanone
Product Type Chemical
Properties
Formula C17H14O3
MW 266.29
CAS 50632-57-0
Source/Host Chemicals Synthetic
Purity Chemicals ≥98% (HPLC)
Appearance White to off-white solid.
Solubility Soluble in acetonitrile, methanol or chloroform.
Identity Determined by 1H-NMR.
Declaration Manufactured by Chemodex.
Other Product Data

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Our product description may differ slightly from the original manufacturers product datasheet.

InChi Key BLWINLJDTOJSRU-UHFFFAOYSA-N
Smiles O=C1C(C2=CC=CC=C2)=COC1(C3=CC=CC=C3)OC
Shipping and Handling
Shipping AMBIENT
Short Term Storage +20°C
Long Term Storage +4°C
Handling Advice Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at +4°C.
Documents
Product Specification Sheet
Datasheet Download PDF
Description
2-Methoxy-2,4-diphenyl-3(2H)-furanone (MDPF) is used as a sensitive fluorescent labeling reagent widely used to derivatize primary and secondary amines on molecules such as proteins. Upon derivatization, it produces highly stable and strongly fluorescent adducts, enabling reliable analysis by HPLC, fluorescence spectroscopy, or imaging techniques. MDPF is commonly applied in bioanalytical chemistry to measure amino acids, peptides, and amine-containing biomolecules, as well as in environmental and pharmaceutical studies for trace amine detection. Spectral Data: λEx=384 nm, λEm=472 nm (in acetonitrile after derivatization with hexylamine).
Product References
(1) S. Stein; Pept. Neurobiol. 9 (1977) | (2) M.A. Fishman, et al.; J. Neurochem. 32, 1077 (1979) | (3) R.L. O'Grady, et al.; Anal. Biochem. 140, 490 (1984) | (4) P. Jackson, et al.; Electrophoresis 9, 330 (1988) | (5) M. Hengstschlager, et al.; Cytometry 14, 39 (1993) | (6) J.C. Stockert & C.I. Trigoso; Blood Cells 19, 423 (1993) | (7) F.J. Alba, et al.; Electrophoresis 18, 1960 (1998) | (8) J.R. Daban; Electrophoresis 22, 874 (2001) | (9) K. Martin, et al.; Proteomics 3, 1215 (2003) | (10) D. Min, et al.; Electrophoresis 27, 357 (2006)
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