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Chemodex
Myricetin
54
CHF
CHF 54.00
In stock
CDX-M0504-M02525 mgCHF 54.00
CDX-M0504-M100100 mgCHF 135.00
| Product Details | |
|---|---|
| Synonyms | 3,3',4',5,5',7-Hexahydroxyflavone; Cannabiscetin; Myricetol; NSC 407290 |
| Product Type | Chemical |
| Properties | |
| Formula |
C15H10O8 |
| MW | 318.24 |
| CAS | 529-44-2 |
| RTECS | LK8646000 |
| Source/Host Chemicals | Plant |
| Purity Chemicals | ≥98% (HPLC) |
| Appearance | Yellow powder. |
| Solubility | Soluble in DMSO (10mg/ml), DMF (10mg/ml) or ethanol (2mg/ml). |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | IKMDFBPHZNJCSN-UHFFFAOYSA-N |
| Smiles | OC1=C2C(OC(C3=CC(O)=C(O)C(O)=C3)=C(O)C2=O)=CC(O)=C1 |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
Myricetin is a naturally occurring flavonol with powerful antioxidant property. It also exhibits a wide range of additional effects that include, anticancer, antidiabetic, neuroprotective and anti-inflammatory activities. It is also used as a preserving agent to extend the shelf life of foods containing oils and fats, based on it's ability to protect lipids against oxidation. Myricetin has been shown to suppress cancer cell invasion and metastasis, to induce cell cycle arrest and apoptosis of cancer cells and to inhibit their proliferation. Myricetin inhibits NLRP3 inflammasome activation via reduction of ROS-dependent ubiquitination of ASC and promotion of ROS-independent NLRP3 ubiquitination.
Product References
(1) K.C. Ong & H.E. Khoo; Gen. Pharmacol. 29, 121 (1997) (Review) | (2) K.P. Devi, et al.; Life Sci. 142, 19 (2015) (Review) | (3) D.K. Semwal, et al.; Nutrients 8, 90 (2016) (Review) | (4) M. Jiang, et al.; Biomed. Pharmacother. 120, 109506 (2019) (Review) | (5) H. Chen, et al.; Toxicol. Appl. Pharmacol. 365, 19 (2019)