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Chemodex
Mepivacaine hydrochloride
81
CHF
CHF 81.00
In stock
CDX-M0557-M05050 mgCHF 81.00
| Product Details | |
|---|---|
| Synonyms | 1-Methyl-2',6'-pipecoloxylidine hydrochloride; N-(2,6-Dimethylphenyl)-1-methyl-2-piperidinecarboxamide hydrochloride; (±)-Mepivacaine hydrochloride |
| Product Type | Chemical |
| Properties | |
| Formula |
C15H22N2O . HCl |
| MW | 282.81 |
| CAS | 1722-62-9 |
| RTECS | TK6475000 |
| Purity Chemicals | ≥98% (HPLC) |
| Appearance | White to beige powder. |
| Solubility | Soluble in water (20mg/ml). |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | RETIMRUQNCDCQB-UHFFFAOYSA-N |
| Smiles | CC1=CC=CC(C)=C1NC(C2N(C)CCCC2)=O.Cl |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +20°C |
| Long Term Storage | +20°C |
| Handling Advice | Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at RT. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
Mepivacaine hydrochloride is a long-acting local anesthetic that reversibly blocks transient Na+ inward current, as well as the steady-state K+ outward current. Mepivacaine blocks tandem pore (TASK) and Kv1.5 potassium channels in model systems.
Product References
(1) F.P. Luduena, et al.; Toxicol. Appl. Pharmacol. 2, 295 (1960) | (2) M. Sadove & G.D. Wessinger; J. Int. Coll. Surg. 34, 573 (1960) | (3) A. El-Maghraby, et al.; J. Egypt Med. Assoc. 47, 153 (1964) | (4) A.G. Burm, et al.; Anesth. Analg. 84, 85 (1997) | (5) V. Tagariello, et al.; Minerva Anestesiol. 67, 5 (2001) (Review) | (6) A. Leffler, et al.; Eur. J. Pharmacol. 630, 19 (2010) | (7) W.G. Brockmann; Gen. Dent. 62, 70 (2014) (Review)