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Chemodex
4-Methylumbelliferyl α-L-fucopyranoside
As low as
322
CHF
CHF 322.00
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CDX-M0587-M01010 mgCHF 322.00
CDX-M0587-M02525 mgCHF 606.00
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| Product Details | |
|---|---|
| Synonyms | 4-Methylumbelliferyl α-L-fucoside; 4-Methylumbelliferyl α-L-fucopyranoside; 4-?U-α-L-Fucopyranoside |
| Product Type | Chemical |
| Properties | |
| Formula | C16H18O7 |
| MW | 322.31 |
| CAS | 54322-38-2 |
| Source/Host Chemicals | Synthetic |
| Purity Chemicals | ≥98% (HPLC) |
| Appearance | White solid. |
| Solubility | Soluble in DMF (20mg/ml). |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | CQKHENXHLAUMBH-CRLRYRHBSA-N |
| Smiles | C[C@@H]1O[C@@H](OC2=CC=C(C(C)=CC(O3)=O)C3=C2)[C@@H](O)[C@H](O)[C@@H]1O |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
4-Methylumbelliferyl-α-L-fucopyranoside is a non-fluorescent but fluorogenic substrate for α-L-fucosidase (FUCA1) yielding a blue fluorescent solution. It is a fluorogenic MU substrate for detecting α-L-fucosidase in cell extracts and purified enzyme preparations using a fluorescence microplate reader or fluorometer. Hydrolysis of 4-Methylumbelliferyl-α-L-fucopyranoside releases the fluorescent product 4-MU. Spectral Data. λEx/λEm= 360/450 nm (cleaved product, pH-dependent).
Product References
(1) D. Robinson & R. Thorpe; Clin. Chim. Acta 55, 65 (1974) | (2) J.A. Alhadeff, et al.; Clin. Chim. Acta 57, 307 (1974) | (3) R.L. Hopfer, et al.; Biochem. J. 266, 491 (1990) | (4) G.Y. Wiederschain, et al.; Carbohydr. Res. 224, 255 (1992) | (5) H. Takeshita, et al.; Hum. Genet. 94, 224 (1994) | (6) S. Khunsook, et al.; Mol. Hum. Reprod. 8, 221 (2002) | (7) C. Li, et al.; World J. Gastroenterol. 12, 3770 (2006)