Cookie Policy: This site uses cookies to improve your experience. You can find out more about our use of cookies in our Privacy Policy. By continuing to browse this site you agree to our use of cookies.
Chemodex
Methansulfonic anhydride
Product Details | |
---|---|
Synonyms | Mesyl anhydride; Ms2O; NSC65906 |
Product Type | Chemical |
Properties | |
Formula | C2H6O5S2 |
MW | 174.2 |
CAS | 7143-01-3 |
Source/Host Chemicals | Synthetic. |
Purity Chemicals | ≥97% (T) |
Appearance | White to light grey to brown powder. |
Solubility | Soluble in DMSO or chloroform. |
Identity | Determined by 1H-NMR. |
Declaration | Manufactured by Chemodex. |
Other Product Data |
Click here for Original Manufacturer Product Datasheet |
InChi Key | IZDROVVXIHRYMH-UHFFFAOYSA-N |
Smiles | CS(=O)(OS(=O)(C)=O)=O |
Shipping and Handling | |
Shipping | AMBIENT |
Short Term Storage | +20°C |
Long Term Storage | +20°C |
Handling Advice | Protect from light and moisture. |
Use/Stability | Stable for at least 2 years after receipt when stored at RT. |
Documents | |
MSDS | Inquire |
Product Specification Sheet | |
Datasheet | Download PDF |
Methanesulfonic anhydride is a building block for organic synthesis. It is used to prepare methylsulfonyl esters, also called as mesylates. It finds application in the reaction of aromatic alkylation. It reacts with dimethylsulfoxide to get sulfoxonium complex, which is a useful oxidizing agent. It is a more powerful sulfonylating reagent than the sulfonyl chloride. Used in the synthesis of (R)-Amino Carnitine, an inhibitor of fatty acid oxidation.
[1] K. Smith, et al.; Org. Biomol. Chem. 2, 3150 (2004) | [2] M.C. Wilkinson; Org. Lett. 13, 2232 (2011) | [3] W. Liu, & T.D. Tilley; Langmuir 31, 1189 (2015) | [4] Y. Hu, et al.; Med. Chem. 5, 354 (2015) | [5] M. Hasani, et al.; J. Phys. Chem. B, 123, 1815 (2019)