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Chemodex
1-(6-Methoxy-2-naphthyl)ethanol
Product Details | |
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Synonyms | Naproxen Impurity K (Ph.Eur); MNE; α-(6-Methoxy-2-naphthyl)-ethanol; (±)-1-(6-Methoxy-2-naphthyl)-ethanol; 2-(1-Hydroxyethyl)-6-methoxynaphthalin; 6-Methoxy-α-methyl-2-naphthalinmethanol |
Product Type | Chemical |
Properties | |
Formula | C13H14O2 |
MW | 202.25 |
CAS | 77301-42-9 |
Source/Host Chemicals | Synthetic |
Purity Chemicals | ≥98% (HPLC) |
Appearance | White to off-white powder or crystals. |
Solubility | Soluble in DMSO, DMF, ethanol (all 30mg/ml) or chloroform. |
Identity | Determined by 1H-NMR. |
Declaration | Manufactured by Chemodex. |
Other Product Data |
Click here for Original Manufacturer Product Datasheet |
InChi Key | OUVJWFRUESFCCY-UHFFFAOYSA-N |
Smiles | CC(C1=CC2=C(C=C1)C=C(C=C2)OC)O |
Shipping and Handling | |
Shipping | AMBIENT |
Short Term Storage | +4°C |
Long Term Storage | +4°C |
Handling Advice | Protect from light and moisture. |
Use/Stability | Stable for at least 2 years after receipt when stored at +4°C. |
Documents | |
MSDS | Inquire |
Product Specification Sheet | |
Datasheet | Download PDF |
The metabolite (1RS)-1-(6-Methoxy-2-naphthyl)ethanol (Naproxen Impurity K) is a photo-degradation product from Naproxen which is a non-steroidal anti-inflammatory drug (NSAID) used to in the treatment of pain, menstrual cramps, inflammatory diseases such as rheumatoid arthritis, gout and fever. Ibuprofen is an anti-inflammatory COX inhibitor. This product can be used as a working standard or secondary analytical reference standard or as an organic building block and intermediate for synthesis.
(1) A. Ekpe, et al.; J. Chromatogr. Sci. 39, 81 (2001) | (2) L. Monser & F. Darghouth; J. Pharma. Biomed. Anal. 32, 1087 (2003) | (3) M. Valero & C Carrillo; J. Photochem. Photobiol. B: Biol. 74, 151 (2004) | (4) M. Isidori, et al.; Sci. The Total Env. 348, 93 (2005) | (5) R.S. Reddy, et al.; TACL 6, 55 (2016) | (6) N. Cazzaniga, et al.; Eur. J. Mass Spectr. 26, 400 (2020)