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Chemodex
N,N-Bis(phosphonomethyl)glycine
88
CHF
CHF 88.00
In stock
CDX-N0054-G01010 gCHF 88.00
CDX-N0054-G05050 gCHF 353.00
| Product Details | |
|---|---|
| Synonyms | N-(Carboxymethyl)iminodi(methylphosphinic acid); Glyphosine; Glycine-N,N-bis(methylenephosphonic acid); BRN 1884944; Polaris |
| Product Type | Chemical |
| Properties | |
| Formula | C4H11NO8P2 |
| MW | 263.08 |
| CAS | 2439-99-8 |
| RTECS | MB9120000 |
| Source/Host Chemicals | Synthetic |
| Purity Chemicals | ≥98% (T) |
| Appearance | Off-white to beige powder. |
| Solubility | Soluble in water (20mg/ml). Insoluble in organic solvents. |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | OXHDYFKENBXUEM-UHFFFAOYSA-N |
| Smiles | O=P(O)(O)CN(CP(O)(O)=O)CC(O)=O |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +20°C |
| Long Term Storage | +4°C |
| Handling Advice | Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at +4°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
A glycine-phosphonic acid compound, negatively charged at neutral pH, with immunomodulatory and anti-diabetic properties. Enhances anti-B:9-23 TCR-dependent T cell activation by modulating murine class II MHC I-Ag7-mediated B:9-23 presentation on APCs. Daily administration of glyphosine is shown to delay the onset of diabetes in NOD mice. Herbicide. A plant growth regulator. Acts as a competitive inhibitor of phoshoenolpyruvate carboxylase in plants.
Product References
(1) F.E. Podesta, et al.; Plant Cell Physiol. 28, 375 (1987) | (2) M. Galanski, et al.; J. Med. Chem. 46, 4946 (2003) | (3) B.D. Stadinski, et al.; PNAS 107, 10978 (2010) | (4) A.W. Michels, et al.; J. Immunol. 187, 5921 (2011)