Cookie Policy: This site uses cookies to improve your experience. You can find out more about our use of cookies in our Privacy Policy. By continuing to browse this site you agree to our use of cookies.
Chemodex
Norfloxacin
As low as
26
CHF
CHF 26.00
In stock
Only %1 left
CDX-N0101-G0011 gCHF 26.00
CDX-N0101-G0055 gCHF 52.00
NEW
Specifications / Handling
| Product Details | |
|---|---|
| Synonyms | 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid; AM715; MK0366; N-Demethylpefloxacin; Baccidal; Noflo |
| Product Type | Chemical |
| Properties | |
| Formula | C16H18FN3O3 |
| MW | 319.33 |
| CAS | 70458-96-7 |
| RTECS | VB2005000 |
| Source/Host Chemicals | Synthetic |
| Purity Chemicals | ≥98% (HPLC) |
| Appearance | White to off-white powder or crystals. |
| Solubility | Soluble in DMSO (2mg/ml) or DMF (5 mg/ml). |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | OGJPXUAPXNRGGI-UHFFFAOYSA-N |
| Smiles | O=C(O)C1=CN(C2=CC(=C(F)C=C2C1=O)N3CCNCC3)CC |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +20°C |
| Long Term Storage | +4°C |
| Handling Advice | Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at +4°C. |
| Documents | |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Scientific Background Information
Product Description
Norfloxacin is a synthetic fluoroquinolone antibiotic with broad-spectrum activity against a wide range of Gram-negative and selected Gram-positive bacteria. It acts by inhibiting bacterial DNA gyrase and topoisomerase IV (enzymes critical for bacterial DNA supercoiling and segregation), thereby blocking DNA replication and cell division. Norfloxacin is widely used to investigate antibacterial mechanisms, bacterial physiology, antimicrobial resistance and drug susceptibility. It also serves as a valuable analytical reference standard for pharmaceutical, environmental, and microbiological studies. It may be used as a standard in the determination of norfloxacin in human serum samples using fluorometric spectrophotometry.
Product-specific References
(1) B. Holmes, et al.; Drugs 30, 482 (1985) (Review) | (2) E.J. Goldstein; Am. J. Med. 82, 3 (1987) (Review) | (3) L. Miano, et al.; Eur. Urol. 17, 13 (1990) (Review) | (4) L. Chierentin & H.R. Salgado; Crit. Rev. Anal. Chem. 46, 22 (2016) (Review) | (5) A. Khanna, et al.; Bioorg. Chem. 153, 107773 (2024) (Review) | (6) A. Khanna, et al.; Future Med. Chem. 17, 1739 (2025) (Review)