Chemodex

4-Nitrophenyl decanoate

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Specifications / Handling

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Product Details
Synonyms 4-NPD; 4-Nitrophenyl caprate; p-Nitrophenyl decanoate; p-NPD; Decanoic acid 4-nitrophenyl ester
Product Type Chemical
Properties
Formula C16H23NO4
MW 293.36
CAS 1956-09-8
Source/Host Chemicals Synthetic
Purity Chemicals ≥98% (TLC)
Appearance Off-white crystals.
Solubility Soluble in chloroform (100mg/ml).
Identity Determined by 1H-NMR.
Declaration Manufactured by Chemodex.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

InChi Key RRNKCSIEGPOIKI-UHFFFAOYSA-N
Smiles CCCCCCCCCC(=O)Oc1ccc(cc1)[N+]([O-])=O
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
Product Specification Sheet
Datasheet Download PDF Download PDF

Scientific Background Information

Product Description
4-Nitrophenyl decanoate is a chromogenic long-chain fatty acid ester substrate widely used in enzymology and biochemical research for the characterization of lipase and esterase activity. Upon enzymatic hydrolysis, it releases 4-nitrophenol, which can be converted to p-nitrophenoxide under alkaline conditions and quantified spectrophotometrically by monitoring its absorbance at approximately 405 nm. Due to its hydrophobic decanoate chain, 4-nitrophenyl decanoate is particularly suitable for studying enzymes involved in the hydrolysis of long-chain lipid substrates, including lipases, esterases, and related hydrolases. The extracellular lipase has greater hydrolysis reaction velocity with 4-nitrophenyl decanoate when compared with other 4-nitropheny esters.
Product-specific References
(1) P.A. Munoz, et al.; Lipids 48, 527 (2013) | (2) P. Ascenzi, et al.; PLoS One 10, e0120603 (2015) | (3) A. Kotogan, et al.; Int. J. Mol. Sci. 19, 1129 (2018)
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