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Chemodex
S-Nitrosoglutathione
As low as
41
CHF
CHF 41.00
In stock
Only %1 left
CDX-N0262-M01010 mgCHF 41.00
CDX-N0262-M05050 mgCHF 162.00
Specifications / Handling
| Product Details | |
|---|---|
| Synonyms | GSNO; SNOG |
| Product Type | Chemical |
| Properties | |
| Formula |
C10H16N4O7S |
| MW | 336.32 |
| CAS | 57564-91-7 |
| Purity Chemicals | ≥97% (NMR) |
| Appearance | Pale pink powder. |
| Solubility | Soluble in water (20 mg/ml) or DMSO (20mg/ml). |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | HYHSBSXUHZOYLX-WDSKDSINSA-N |
| Smiles | OC([C@@H](N)CCC(N[C@H](C(NCC(O)=O)=O)CSN=O)=O)=O |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Scientific Background Information
Product Description
S-Nitroso-L-glutathione is an S-nitrosothiol NO donor based on naturally-occurring glutathione. It is a potent smooth muscle relaxant and inhibitor of platelet aggregation. Its stability in solution varies from seconds to hours depending on temperature, buffer composition and metal content.
Product-specific References
(1) M.W. Radomski, et al.; Br. J. Pharmacol. 107, 745 (1992) | (2) W.R. Mathews & S.W. Kerr; J. Pharmacol. Exp. Ther. 267, 1529 (1993) | (1) E.A. Konorev, et al.; J. Pharmacol. Exp. Ther. 274, 200 (1995) | (4) A. Gasco, et al.; Farmaco 51, 617 (1996) | (5) J.A. Cook, et al.; Anal. Biochem. 238, 150 (1996) | (6) A.R. Butler & P. Rhodes; Anal. Biochem. 249, 1 (1997) | (7) R. Motterlini, et al.; J. Biol. Chem. 275, 13613 (2000) | (8) H. K. Jeon, et al.; Cell. Biol. Toxicol. 21, 115 (2005) | (9) C.X. Yu, et al.; Mol. Pharmacol. 68, 847 (2005) | (10) M. Khan, et. al.; J. Cereb. Blood Flow Metab. 25, 177 (2005) | (11) D. McGrowder, et al.; J. Biosci. 31, 347 (2006) | (12) R. Prasad, et al.; Glia 55, 65 (2007) | (13) M. Mussbacher, et al.; Sci. Rep. 9, 15403 (2019)