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Chemodex
S-Nitrosoglutathione
41
CHF
CHF 41.00
In stock
CDX-N0262-M01010 mgCHF 41.00
CDX-N0262-M05050 mgCHF 162.00
| Product Details | |
|---|---|
| Synonyms | GSNO; SNOG |
| Product Type | Chemical |
| Properties | |
| Formula |
C10H16N4O7S |
| MW | 336.32 |
| CAS | 57564-91-7 |
| Purity Chemicals | ≥97% (NMR) |
| Appearance | Pale pink powder. |
| Solubility | Soluble in water (20 mg/ml) or DMSO (20mg/ml). |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | HYHSBSXUHZOYLX-WDSKDSINSA-N |
| Smiles | OC([C@@H](N)CCC(N[C@H](C(NCC(O)=O)=O)CSN=O)=O)=O |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
S-Nitroso-L-glutathione is an S-nitrosothiol NO donor based on naturally-occurring glutathione. It is a potent smooth muscle relaxant and inhibitor of platelet aggregation. Its stability in solution varies from seconds to hours depending on temperature, buffer composition and metal content.
Product References
(1) M.W. Radomski, et al.; Br. J. Pharmacol. 107, 745 (1992) | (2) W.R. Mathews & S.W. Kerr; J. Pharmacol. Exp. Ther. 267, 1529 (1993) | (1) E.A. Konorev, et al.; J. Pharmacol. Exp. Ther. 274, 200 (1995) | (4) A. Gasco, et al.; Farmaco 51, 617 (1996) | (5) J.A. Cook, et al.; Anal. Biochem. 238, 150 (1996) | (6) A.R. Butler & P. Rhodes; Anal. Biochem. 249, 1 (1997) | (7) R. Motterlini, et al.; J. Biol. Chem. 275, 13613 (2000) | (8) H. K. Jeon, et al.; Cell. Biol. Toxicol. 21, 115 (2005) | (9) C.X. Yu, et al.; Mol. Pharmacol. 68, 847 (2005) | (10) M. Khan, et. al.; J. Cereb. Blood Flow Metab. 25, 177 (2005) | (11) D. McGrowder, et al.; J. Biosci. 31, 347 (2006) | (12) R. Prasad, et al.; Glia 55, 65 (2007) | (13) M. Mussbacher, et al.; Sci. Rep. 9, 15403 (2019)