N-(3-Oxotetradecanoyl)-DL-homoserine lactone

CHF 64.00
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CDX-O0055-M01010 mgCHF 64.00
CDX-O0055-M100100 mgCHF 357.00
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Product Details
Synonyms 3-oxo-C14-HSL; 3OC14-HSL; N-3-oxo-Myristoyl-DL-Homoserine lactone
Product Type Chemical
Formula C18H31NO4
MW 325.4
CAS 503610-29-5
Source/Host Chemicals Synthetic.
Purity Chemicals ≥97% (GC)
Appearance White solid.
Solubility Soluble in chloroform.
Identity Determined by NMR.
Declaration Manufactured by Chemodex.
Other Product Data

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Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Keep cool and dry.
Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
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Product Specification Sheet
Datasheet Download PDF
N-(3-Oxotetradecanoyl)-DL-homoserine lactone is a small diffusible signaling molecule and is a member of N-acyl-homoserine lactone family. N-acylhomoserine lactones (AHL) are involved in quorum sensing, controlling gene expression, and cellular metabolism. The diverse applications of this kind of molecule include regulation of virulence in general, infection prevention, and formation of biofilms. It appears later than shorter acyl chain AHLs in developing biofilms and like other long chain 3-oxo-AHLs, stimulates the production of putisolvin, which in turn inhibits biofilm formation.
Product References
(1) A. Kuo, et al.; J. Bacteriol. 176, 7558 (1994) | (2) A.L. Schaefer, et al.; J. Bacteriol. 178, 2897 (1996) | (3) K.H. McClean, et. al.; Microbiol. 143, 3703 (1997) | (4) J.K. Lithgow, et al.; Mol. Microbiol. 37, 81 (2000) | (5) S.R. Chhabra, et al.; J. Med. Chem. 46, 97 (2003) | (6) J.F. Dubern, et al.; J. Bacteriol. 188, 2898 (2006) | (7) A.M. Pomini & A.J. Marsaioli; J. Nat. Prod. 71, 1032 (2008) | (8) B.M. Davis, et al.; Biophy. J. 101, 245 (2011)
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