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Chemodex
N-(3-Oxotetradecanoyl)-DL-homoserine lactone
68
CHF
CHF 68.00
In stock
CDX-O0055-M01010 mgCHF 68.00
CDX-O0055-M100100 mgCHF 380.00
| Product Details | |
|---|---|
| Synonyms | 3-oxo-C14-HSL; 3OC14-HSL; N-3-oxo-Myristoyl-DL-Homoserine lactone |
| Product Type | Chemical |
| Properties | |
| Formula | C18H31NO4 |
| MW | 325.4 |
| CAS | 503610-29-5 |
| Source/Host Chemicals | Synthetic. |
| Purity Chemicals | ≥97% (GC) |
| Appearance | White solid. |
| Solubility | Soluble in chloroform. |
| Identity | Determined by NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | YQFJJDSGBAAUPW-UHFFFAOYSA-N |
| Smiles | CCCCCCCCCCCC(=O)CC(=O)NC1CCOC1=O |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice |
Keep cool and dry. Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
N-(3-Oxotetradecanoyl)-DL-homoserine lactone is a small diffusible signaling molecule and is a member of N-acyl-homoserine lactone family. N-acylhomoserine lactones (AHL) are involved in quorum sensing, controlling gene expression, and cellular metabolism. The diverse applications of this kind of molecule include regulation of virulence in general, infection prevention, and formation of biofilms. It appears later than shorter acyl chain AHLs in developing biofilms and like other long chain 3-oxo-AHLs, stimulates the production of putisolvin, which in turn inhibits biofilm formation.
Product References
(1) A. Kuo, et al.; J. Bacteriol. 176, 7558 (1994) | (2) A.L. Schaefer, et al.; J. Bacteriol. 178, 2897 (1996) | (3) K.H. McClean, et. al.; Microbiol. 143, 3703 (1997) | (4) J.K. Lithgow, et al.; Mol. Microbiol. 37, 81 (2000) | (5) S.R. Chhabra, et al.; J. Med. Chem. 46, 97 (2003) | (6) J.F. Dubern, et al.; J. Bacteriol. 188, 2898 (2006) | (7) A.M. Pomini & A.J. Marsaioli; J. Nat. Prod. 71, 1032 (2008) | (8) B.M. Davis, et al.; Biophy. J. 101, 245 (2011)
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