Cookie Policy: This site uses cookies to improve your experience. You can find out more about our use of cookies in our Privacy Policy. By continuing to browse this site you agree to our use of cookies.
Chemodex
N-(3-Oxoundecanoyl)-L-homoserine lactone
68
CHF
CHF 68.00
In stock
CDX-O0140-M01010 mgCHF 68.00
CDX-O0140-M05050 mgCHF 272.00
| Product Details | |
|---|---|
| Synonyms | 3-oxo-C11-L-HSL; 3-oxo-N-[(3S)-2-oxooxolan-3-yl]undecanamide |
| Product Type | Chemical |
| Properties | |
| Formula | C15H25NO4 |
| MW | 283.4 |
| CAS | 216596-70-2 |
| Source/Host Chemicals | Synthetic |
| Purity Chemicals | ≥97% (HPLC) |
| Appearance | White to off-white powder. |
| Solubility | Soluble in DMSO or chloroform. |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | SELZAQGRPYIEQS-ZDUSSCGKSA-N |
| Smiles | O=C1[C@@H](NC(CC(CCCCCCCC)=O)=O)CCO1 |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
N-(3-Oxoundecanoyl)-L-homoserine lactone is a small diffusible signaling molecule and is a member of N-acyl-homoserine lactone family. N-acylhomoserine lactones (AHL) are involved in quorum sensing, controlling gene expression, and cellular metabolism. The diverse applications of this kind of molecule include regulation of virulence in general, infection prevention, and formation of biofilms. Numerous species of bacteria employ 3OC11-HSL in cell-to-cell communication. Shown to have immune suppressive activity, inhibiting murine and human leucocyte proliferation.
Product References
(1) S.R. Chhabra, et al.; J. Med. chem. 46, 97 (2003) | (2) J. Zhu, et al.; Appl. Environ. Microbiol. 69, 6949 (2003) | (3) C.L. Weingart, et al.; Mol. Microbiol. 57, 452 (2005) | (4) S.-A. Alexander, et al.; Chem. Commun. 51, 3355 (2015)