Physil chloride

CHF 63.00
In stock
CDX-P0009-M05050 mgCHF 63.00
CDX-P0009-M250250 mgCHF 162.00
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Product Details
Synonyms 4-(N-Phthalimidyl)-benzenesulfonyl chloride
Product Type Chemical
Formula C14H10ClNO3S
MW 307.75
CAS 114341-14-9
Source/Host Chemicals Synthetic.
Purity Chemicals ≥98% (HPLC)
Appearance Solid.
Solubility Soluble in acetone.
Identity Determined by 1H-NMR.
Declaration Manufactured by Chemodex.
Other Product Data

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Our product description may differ slightly from the original manufacturers product datasheet.

Smiles ClS(=O)(=O)C1=CC=C(C=C1)N1CC2=CC=CC=C2C1=O
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage +4°C
Handling Advice Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at +4°C.
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Product Specification Sheet
Datasheet Download PDF
It is known that phenol and p-cresol are promoters of skin tumors and also urinary excretion of phenol and p-cresol is increased by exposure to benzene, which has hemopoietic toxicity, and toluene, respectively. Therefore, the determination of phenol and p-cresol is important in clinical chemistry and toxicology. Because phenol and p-cresol are present in urine as sulfate or glucuronide conjugates, they are hydrolyzed enzymatically or with acid, followed by distillation or extraction with organic solvent prior to measurement by GC or HPLC. However, these GC and HPLC methods require relatively large sample volumes (more than 1 ml) because of their insufficient sensitivities for measuring small amounts of phenol and p-cresol. The application of fluorescent labeling techniques to HPLC result in a sensitive and selective method. Phthalimidylbenzenesulfonyl chlorides habe also been successfully used for high sensitivity labelling of amino acids prior to HPLC.
Product References
(1) Y. Tsuruta et al.; Anal. Biochem. 243, 86 (1996) | (2) Y. Tsuruta et al.; J. Chromatogr. 502, 178 (1990) | (3) O.M. Bakke et al.; Toxicol. Appl. Pharmacol. 16, 691 (1970) | (4) C.N. Ong et al.; J. Chromatogr. 660, 1 (1959) | (5) R. Boutwell et al.; Cancer Res. 19, 413 (1959)
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