Phenol red sodium salt

CHF 26.00
In stock
CDX-P0026-G0011 gCHF 26.00
CDX-P0026-G01010 gCHF 70.00
CDX-P0026-G05050 gCHF 211.00
More Information
Product Details
Synonyms 4,4'-(1,1-Dioxido-3H-2,1-benzoxathiol-3-ylidene)bis-phenol sodium salt
Product Type Chemical
Properties
Formula C19H13O5S . Na
MW 376.36
CAS 34487-61-1
Source/Host Chemicals Synthetic
Purity Chemicals Dye content 90 % (Titration)
Appearance Red to brown powder.
Solubility Soluble in water.
Identity Determined by 1H-NMR.
Declaration Manufactured by Chemodex.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

InChi Key RBFZWTMVVUVHLM-UHFFFAOYSA-M
Smiles [Na+].OC1=CC=C(C=C1)C(=C1C=CC(=O)C=C1)C1=CC=CC=C1S([O-])(=O)=O
Shipping and Handling
Shipping AMBIENT
Short Term Storage +20°C
Long Term Storage +20°C
Handling Advice Keep cool and dry.
Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at +20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF

Water soluble pH indicator used in the 6.8 (yellow) to 8.2 (red) range and frequently used in cell biology laboratories. Widely used as cell tissue culture pH marker. A small amount of phenol red added to the growth medium will have a pink-red color under normal conditions. Typically, 15 mg/l are used for cell culture. In the event of problems, waste products produced by dying cells or overgrowth of contaminants will cause a change in pH, leading to a change in indicator color. For example, a culture of relatively slowly dividing mammalian cells can be quickly overgrown by bacterial contamination. This usually results in an acidification of the medium, turning it yellow. The waste products produced by the mammalian cells themselves will slowly decrease the pH, gradually turning the solution orange and then yellow. This color change is an indication that even in the absence of contamination, the medium needs to be replaced. Shown to be a weak estrogen mimic (possible through inpurities), which can enhance the growth of cells that express the estrogen receptor in cell cultures. Might be useful as a differentiation factor.

Product References

(1) F.L. Rodkey; Arch. Biochem. Biophys. 94, 38 (1961) | (2) T. Hoshi & H. Hayashi; Jpn. J. Physiol. 20, 683 (1970) | (3) U. Kragh-Hansen & J.V. Moller; Biochim. Biophys. Acta 295, 438 (1973) | (4) Y. Berthois, et al.; PNAS 83, 2496 (1986) | (5) P. Yuan & D.R. Walt; J. Fluoresc. 2, 231 (1992) | (6) L. Hopp & C.H. Bunker; J. Cell Physiol. 157, 594 (1993) | (7) J. Wesierska-Gadek, et al.; Cell Mol. Biol. Lett. 12, 280 (2007) | (8) H. Lysdahl, et al.; Stem Cell Rev. 9, 132 (2013)

© 2017 Adipogen Life Sciences. Pictures: © 2012 Martin Oeggerli. All Rights Reserved.