Chemodex

Poly[(R)-3-hydroxybutyric acid] (natural origin)

CHF 88.00
In stock
CDX-P0074-G01010 gCHF 88.00
CDX-P0074-G100100 gCHF 482.00
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Product Details
Synonyms (R)-3-Hydroxybutyric acid polymerized; PHB; Polyhydroxybutyrate
Product Type Chemical
Properties
Formula [COCH2CH(CH3)O]n
MW 104.1
CAS 29435-48-1
Source/Host Chemicals Synthetic
Appearance Beige powder.
Solubility Soluble in chloroform.
Declaration Manufactured by Chemodex.
Other Product Data

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Our product description may differ slightly from the original manufacturers product datasheet.

Shipping and Handling
Shipping AMBIENT
Short Term Storage +20°C
Long Term Storage +20°C
Handling Advice Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at RT.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
Description

PHB is a fully biodegradable polyester with optical activity, piezoelectricity, and very good barrier properties. PHB is a partially crystalline material with a high melting temperature and a high degree of crystallinity. PHB is a thermoplastic, belonging to the family of polyhydroxyalkanoate PHAs. It has physical- and mechanical properties comparable to those of isotactic polypropylene iPP. Different bacterial types of microorganisms produce PHB from renewable sources from sugar and molasses as intracellular storage materials. It can be used in applications of drug-loaded medical devices and microspheres as implantable and injectable therapeutic systems in medicine for treatment of various diseases. Besides application of PHB for producing of medical devices and systems of sustained drug delivery, PHB can be used for production of systems for controlled release of activators or inhibitors of enzymes. The use of these systems allows the development of the physiological models for prolonged local activation or inhibition of enzymes in vivo. The PHB is a perspective tool in design of novel physiological models due to minimal adverse inflammatory tissue reaction to PHB matrixes implantation or PHB microspheres administration.

Product References

(1) D. Seebach & M. Zueger; Helv. Chim. Acta 65, 495 (1982) | (2) D. Seebach, et al.; Org. Synth. 71, 39 (1993) | (3) A.P. Bonartsev, et al.; Progr. Org. Phys. Chem. 2013, 183 (2013) | (4) R. Rebois, et al.; Anal. Bioanal. Chem. 409, 2353 (2017) | (5) S. Jurczyk, et al.; Polym. Test. 63, 614 (2017) | (6) R.V. Chemozem, et al.; Mat. Lett. 220, 257 (2018)

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