Parecoxib

CHF 166.00
In stock
CDX-P0167-M02525 mgCHF 166.00
More Information
Product Details
Synonyms N-[[4-(5-Methyl-3-phenyl-4-isoxazolyl)phenyl]sulfonyl]propanamide; Dynastat; SC-69124
Product Type Chemical
Properties
Formula C19H18N2O4S
MW 370.4
CAS 198470-84-7
Source/Host Chemicals Synthetic.
Purity Chemicals ≥98% (HPLC)
Appearance White powder.
Solubility Soluble in water.
Identity Determined by 1H-NMR.
Declaration Manufactured by Chemodex.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

InChi Key TZRHLKRLEZJVIJ-UHFFFAOYSA-N
Smiles O=C(CC)NS(=O)(C1=CC=C(C2=C(C)ON=C2C3=CC=CC=C3)C=C1)=O
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Keep cool and dry.
Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS Inquire
Product Specification Sheet
Datasheet Download PDF

Potent and selective COX-2 inhibitor. Water-soluble amide prodrug of the cyclooxygenase II (COX-2) selective, non-steroidal anti-inflammatory drug (NSAID) valdecoxib. Has anti-inflammatory, analgesic, and antipyretic activities. Upon administration, parecoxib is hydrolyzed by hepatic carboxyesterases to its active form, valdecoxib.

Product References

(1) J.J. Talley, et al.; J. Med. Chem. 43, 1661 (2000) | (2) S.S. Padi, et al.; Eur. J. Pharmacol. 491, 69 (2004) | (3) A.B. Reksidler, et al.; Eur. J. Pharmacol. 560, 163 (2007) | (4) A. Abbate, et al.; J. Cardiovasc. Pharmacol. 49, 416 (2007) | (5) H. Schroeder, et al.; Neurochem. Int. 58, 9 (2011) | (6) Z. Ye, et al.; Neurochem. Res. 37, 321 (2012) | (7) S.J.Chong, et al.; Int. J. Inflam. 2014, 972645 (2014)

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