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Chemodex
Protodioscin
102
CHF
CHF 102.00
In stock
CDX-P0451-M01010 mgCHF 102.00
| Product Details | |
|---|---|
| Synonyms | NSC 698796 |
| Product Type | Chemical |
| Properties | |
| Formula |
C51H84O22 |
| MW | 1049.2 |
| CAS | 55056-80-9 |
| Source/Host Chemicals | Plant |
| Purity Chemicals | ≥98% (HPLC) |
| Appearance | White to off-white powder. |
| Solubility | Soluble in DMSO (20mg/ml), DMF (5mg/ml) or ethanol (10mg/ml). |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | LVTJOONKWUXEFR-UEZXSUPNSA-N |
| Smiles | C[C@]12C(C[C@@H](O[C@@](O[C@H](CO)[C@@H](O[C@]3([H])O[C@@H](C)[C@H](O)[C@@H](O)[C@H]3O)[C@@H]4O)([H])[C@@H]4O[C@]5([H])O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)CC2)=CC[C@]6([H])[C@]1([H])CC[C@@]7(C)[C@@]6([H])C[C@@]8([H])[C@]7([H])[C@H](C)[C@@](O)(CC[C@@H](C)CO[C@@H]9O[C@H](CO)[C@@H](O)[C@H](O)[C@H]9O)O8 |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +20°C |
| Long Term Storage | +4°C |
| Handling Advice | Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at +4°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
Protodioscin is a steroidal saponin first isolated from plants, with anticancer, antihyperlipidemic, antioxidant, anti-inflammatory and neuroprotective properties. It displays cytotoxic, apoptosis incuding and antiproliferative activity against a range of cancer cells. Protodioscin has also been shown to have aphrodisiac properties.
Product References
(1) K. Hu & X. Yao; Planta Med. 68, 297 (2002) | (2) K. Gauthaman, et al.; Life Sci. 71, 1385 (2002) | (3) H. Hibasami, et al.; Int. J. Mol. Med. 11, 23 (2003) | (4) T. Wang, et al.; Planta Med. 76, 1642 (2010) | (5) X. Zhang, et al.; Steroids 113, 52 (2016) | (6) M. Oyama, et al.; Curr. Bioact. Compd. 13, 170 (2017) | (7) J.Y. Liu, et al.; Apoptosis 22, 1454 (2017) | (8) J. Wu, et al.; Pharmacol. Rep. 70, 139 (2018) | (9) C.L. Lin, et al.; Cell Physiol. Biochem. 46, 322 (2018) | (10) K. Shu & Y. Zhang; Cell Stress Chaperones 24, 1091 (2019)