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Chemodex
Quinine hydrochloride dihydrate
90
CHF
CHF 90.00
In stock
CDX-Q0014-G01010 gCHF 90.00
CDX-Q0014-G05050 gCHF 361.00
CDX-Q0014-G100100 gCHF 619.00
| Product Details | |
|---|---|
| Synonyms | (8α, 9R)-6'-Methoxycinchonan-9-ol monohydrochloride dihydrate |
| Product Type | Chemical |
| Properties | |
| Formula |
C20H24N2O2 . HCl . 2H2O |
| MW | 396.91 |
| CAS | 6119-47-7 |
| RTECS | VA7700000 |
| Source/Host Chemicals | Isolated from plant. |
| Purity Chemicals | ≥99% (Titr.) |
| Appearance | White to off-white solid. |
| Solubility | Soluble in water (10mg/ml). |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | LBSFSRMTJJPTCW-DSXUQNDKSA-N |
| Smiles | O[C@H](C1=C(C=C(OC)C=C2)C2=NC=C1)[C@H]3[N@](C[C@@H]4C=C)CC[C@H]4C3.Cl |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +20°C |
| Long Term Storage | +20°C |
| Handling Advice | Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at RT. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
Quinine hydrochloride dihydrate is isolated from the cinchona tree?s bark, is characterized by a bitter taste and shows antipyretic (fever-reducing), anti-malarial, analgesic (painkilling), anti-viral and anti-inflammatory properties. Quinine also possesses, at high concentrations, antibacterial properties, which suggests it has potential as an antimicrobial adjuvant. It is believed to impede the activity of enzymes associated with nucleic acid and protein biosynthesis and act as an antagonist for specific neurotransmitters, including serotonin. Quinine acts as a competitive inhibitor of monoamine oxidase (MAO), an enzyme that removes neurotransmitters from the brain and a general potasssium channel blocker. Quinine is a flavor component of tonic water and bitter lemon drink mixers. Because of its relatively constant and well-known fluorescence quantum yield, quinine sulfate is used in photochemistry as a popular and common fluorescence standard.
Product References
(1) K.A. Conklin & S.C. Chou; Science 170, 1213 (1970) | (2) D.F. Eaton; Pure Appl. Chem. 60, 1107 (1988) | (3) N. Mitsui, et al.; Chem. Pharm. Bull. 37, 363 (1989) | (4) M. Maki, et al.; Biomed. Res. 30, 137 (2009) | (5) J. Achan, et al.; Malar. J. 10, 144 (2011) | (6) F. Islahudin, et al.; Sci. Rep. 4, 3618 (2014) | (7) S. Malakar, et al.; Virus Res. 255, 171 (2018) | (8) Y. Guo, et al.; Luminescence 34, 450 (2019) | (9) K. Nawara & J. Waluk; Anal. Chem. 91, 5389 (2019) | (10) L.G. Leanse, et al.; J. Infect. Dis. 221, 618 (2020) | (11) U.G. Chandrika & U. Karunarathna; Feat. Assessm. Pain Anaesth. Analg. Chaper 5, 47 (2022)