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Chemodex
Resorufin-β-D-glucopyranoside
As low as
284
CHF
CHF 284.00
In stock
Only %1 left
CDX-R0006-M05050 mgCHF 284.00
Specifications / Handling
| Product Details | |
|---|---|
| Synonyms | 3-Phenoxazone 7-(β-D-glucopyranoside) |
| Product Type | Chemical |
| Properties | |
| Formula | C18H17NO8 |
| MW | 375.33 |
| CAS | 101490-85-1 |
| Source/Host Chemicals | Synthetic |
| Purity Chemicals | ≥90% (HPLC) |
| Appearance | Yellow to orange powder. |
| Solubility | Soluble in DMSO (20 mg/ml). Slightly soluble in water. |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | QULZFZMEBOATFS-UYTYNIKBSA-N |
| Smiles | O=C1C=C2OC3=CC(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)=CC=C3N=C2C=C1 |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Scientific Background Information
Product Description
Resorufin-β-D-glucopyranosid is a non-selective red-fluorogenic substrate. It is a fluorogenic substrate for β-glucosidase, β-glucocerebrosidase (GCase) and β-galactosidase. Upon enzymatic cleavage by the enzymes, the fluorescent hydrolysis product resorufin is released and its fluorescence can be used to quantify enzyme activity. Spectral data of Resorufin: λex=571nm, λem=585nm. It is used in several applications, specifically in compound screens, where it is advantageous because it is less prone to compound autofluorescence, and thus produces less false positives.
Product-specific References
(1) O. Motabar, et al.; Anal. Bioanal. Chem. 402, 731 (2012) | (2) S.Ueno, et al.; J. Phtopol. Sci. Technol. 28, 719 (2015) | (3) M.C. Deen, et al.; ACS Chem. Biol. 15, 824 (2020) | (4) A. Gherlein, et al.; Nat. Commun. 14, 2057 (2023)