Ropivacaine

Specifications / Handling

More Information
Product Details
Synonyms	(S)-Ropivacaine; (2S)-N-(2,6-Dimethylphenyl)-1-propyl-2-piperidinecarboxamide
Product Type	Chemical
Properties
Formula	C₁₇H₂₆N₂O
MW	274.4
CAS	84057-95-4
Source/Host Chemicals	Synthetic
Purity Chemicals	≥98% (HPLC)
Appearance	White to off-white powder.
Solubility	Soluble in chloroform or acentonitrile. Slightly soluble in DMSO or methanol.
Identity	Determined by ¹H-NMR.
Declaration	Manufactured by Chemodex.
Other Product Data	Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet.
InChi Key	ZKMNUMMKYBVTFN-UHFFFAOYSA-N
Smiles	CC1=CC=CC(C)=C1NC(C2CCCCN2CCC)=O
Shipping and Handling
Shipping	AMBIENT
Short Term Storage	-20°C
Long Term Storage	-20°C
Handling Advice	Protect from light and moisture.
Use/Stability	Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS	Inquire
Product Specification Sheet
Datasheet	Download PDF

Product-specific References

Description

Ropivacaine is a long-acting amide local anaesthetic agent. Ropivacaine is a potent and reversible blocker of sodium channels in nerve fibers. It is a pure S(-)enantiomer and less lipophilic than racemic sodium channel blockers, such as bupivacaine and is less likely to penetrate large myelinated motor fibres, resulting in a relatively reduced motor blockade. Thus, ropivacaine has a greater degree of motor sensory differentiation, which could be useful when motor blockade is undesirable. The reduced lipophilicity is also associated with decreased potential for central nervous system toxicity and cardiotoxicity.

Product References

(1) R.D. Wang, et al.; Exp. Opin. Pharmacother. 2, 2051 (2001) (Review) | (2) T.G. Hansen; Exp. Rev. Neurother. 4, 781 (2004) (Review) | (3) G. Kuthiala & G. Chaudhary; Indian J. Anaesth. 55, 104 (2011) (Review)

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