Chemodex

Rhodamine B hydrazide

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Product Details
Synonyms 2-Amino-3',6'-bis(diethylamino)-spiro[1H-isoindole-1,9'-[9H]xanthen]-3(2H)-one
Product Type Chemical
Properties
Formula C28H32N4O2
MW 456.59
CAS 74317-53-6
Source/Host Chemicals Synthetic
Appearance Violett crystalline solid.
Solubility Soluble in DMSO (20mg/ml).
Identity Determined by 1H-NMR.
Declaration Manufactured by Chemodex.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturer's product datasheet.

InChi Key WTDHTIVYKKLOTC-UHFFFAOYSA-N
Smiles CCN(CC)C1=CC2=C(C=C1)C3(C(C=CC=C4)=C4C(N3N)=O)C5=CC=C(N(CC)CC)C=C5O2
Shipping and Handling
Shipping AMBIENT
Short Term Storage +20°C
Long Term Storage -20°C
Handling Advice Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
Product Specification Sheet
Datasheet Download PDF
Description
Rhodamine B hydrazide is a water-soluble fluorescent probe. Rhodamine B hydrazide can be used to label biomolecules (e.g., proteins, sugars) that have aldehyde or ketone groups. Spectral Data: λex 510nm, λem 578nm. It has been used for the detection of copper, peroxynitrite, nitric oxide, hydrogen peroxide, glucose, diacetyl, carbonyl, cholesterol and hemoglobin.
Product References
(1) V. Dujols, et al.; JACS 119, 7386 (1997) | (2) X.F. Yang, et al.; Talanta 57, 883 (2002) | (3) X.F. Yang, et al.; Talanta 61, 439 (2003) | (4) X. Chen & Z. Jianli; Microchim. Acta 157, 133 (2007) | (5) Y. Shen, et al.; J. Fluoresc. 18, 163 (2008) | (6) X. Li, et al.; J. Fluoresc. 19, 601 (2009) | (7) C.M. Wu, et al.; Anal. Chim. Acta 708, 141 (2011) | (8) P. Li, et al.; Free Radic. Biol. Med. 65, 224 (2013) | (9) M. Asano, et al.; J. Biosci. Bioeng. 118, 98 (2014) | (10) C.D. Georgiou, et al.; Redox Biol. 17, 236 (2018) | (11) H. Zhang, et al.; Anal. Chem. 97, 4583 (2025)
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