CHF 333.00
In stock
CDX-S0051-M02525 mgCHF 333.00
CDX-S0051-M100100 mgCHF 882.00
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Product Details
Synonyms Revolution; Stronghold; (5Z)-25-Cyclohexyl-4'-O-de(2,6-dideoxy-3-O-methyl-alp.-L-arabino-hexopyranosyl)-5-demethoxy-25-de(1-methylpropyl)-22,23-dihydro-5-(hydroxyimino)avermectin A1a
Product Type Chemical
Formula C43H63NO11
MW 770.0
CAS 220119-17-5
Source/Host Chemicals Synthetic.
Purity Chemicals ≥99% (HPLC)
Appearance Off-white powder.
Solubility Soluble in DMSO, dichloromethane, ethanol or methanol. Slightly soluble in water.
Identity Determined by 1H-NMR.
Declaration Manufactured by Chemodex.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

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Shipping and Handling
Shipping AMBIENT
Short Term Storage +20°C
Long Term Storage +4°C
Handling Advice Keep cool and dry.
Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at +4°C.
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF

Avermectin derivative prepared by hydrolysis and oximation of doramectin. Selamectin is a potent nematocide used for the treatment of parasites that acts as agonist of the GABA (gamma-aminobutyric acid) neurotransmitter in nerve cells and also binds to glutamate-gated chloride channels in nerve and muscle cells of invertebrates. In both cases it blocks the transmission of neuronal signals of the parasites, which are either paralyzed and expelled out of the body, or they starve. It also affects the reproduction of some parasites by diminishing oviposition or inducing an abnormal oogenesis. The substance fights both internal and surface parasitic infection. Compound can be used as analytical reference material.

Antiviral effective against 2019-nCoV

Product References

(1) B.F. Bishop, et al.; Vet. Parasitol. 91, 163 (2000) | (2) R.H. Six, et al.; Vet. Parasitol. 91, 321 (2000) | (3) B.J. Banks, et al.; Bioorg. Med. Chem. 8, 2017 (2000) | (4) J. Griffin, et al.; J. Vet. Pharmacol. Ther. 28, 257 (2005) | (5) M.U. Esatgil, et al.; Pol. J. Vet. Sci. 11, 67 (2008) | (6) M.U. Esatgil, et al.; Pol. J. Vet. Sci. 11, 143 (2008) | (7) J. Geyer, et al.; J. Vet. Pharmacol. Ther. 32, 87 (2009) | (8) A. Melotti, et al.; EMBO Mol. Med. 6, 1263 (2014)

Repurposing of clinically approved drugs for treatment of coronavirus disease 2019 in a 2019-novel coronavirus-related coronavirus model: H.H. Fan, et al.; Chin. Med. J. 133, 1051 (2020)

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